食管早癌及癌前病变的内镜黏膜下剥离术临床疗效及预后随访研究  

Clinical Efficacy and Prognosis Follow-up Study of Endoscopic Submucosal Dissection for Early Esophageal Cancer and Precancerous Lesions

作　　者：孙会潇[1] 陈宏超[1] 王晓霞[1] 陈佩[1] 方立峰[1] 

机构地区：[1]郑州市第一人民医院消化内科,郑州450004

出　　处：《中国医药导刊》2017年第1期21-22,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探究食管早癌及癌前病变的内镜黏膜下剥离术临床疗效及预后随访情况。方法:回顾性分析2010年10月~2014年6月间在我院进行内镜黏膜下剥离术治疗的食管早癌及癌前病变的186例患者的临床资料。结果:164个病灶符合治愈性切除151例(81.59%,164/201);26个病灶符合非治愈性切除24例(12.94%,26/201),其中8个(8例)进一步补充外科手术,3个(3例)术后给予放疗,其余进行跟踪随访;11个(11例)病灶(5.47%,9/201)无法进行评估,全部入组。结论:内镜黏膜下剥离术应用于食管早癌及癌前病变的临床治疗,生存率高、复发率低且并发症发生率低,预后疗效较优。Objective：To investigate the prognosis and follow-up of endoscopic submucosal dissection（ESD） forearly esophageal cancer and precancerous lesions.Methods：The clinical data of 186 patients（201 lesions） who hadbeen diagnosed as early esophageal cancer or precancerous lesions by preoperative biopsy from Jan 2010 to Jun 2011 by ESD were retrospectively analyze.Results：There 151 curative resection patients.There were 26 non-curative resection patients,in which 8 cases were treated with surgical operation,3 cases were given postoperative radiotherapy and the rest were for follow-up.The 11 cases were unable to evaluate,all entered the follow-up group.Conclusion：ESD as one treatment method of early esophageal cancer and precancerous lesions,has long-term low complication rateslow recurrence rateand low survival rate.

关 键 词：食管早癌 内镜黏膜下剥离术 临床疗效 癌前病变 预后 随访 

分 类 号：R735.1[医药卫生—肿瘤]