肺癌根治术后胸部并发症及其危险因素分析  

Analysis of thoracic complications and risk factors in patients with lung cancer radical operation

作　　者：王一北[1] 陈宽冰[1] 张洪岩[1] 石文君[1] 

机构地区：[1]中国医科大学附属盛京医院胸外科,辽宁沈阳110004

出　　处：《现代肿瘤医学》2017年第8期1249-1252,共4页Journal of Modern Oncology

摘　　要：目的:本文旨在探讨肺癌术后胸部并发症的影响因素,为临床提供更多的循证医学证据。方法:回顾性分析2014年6月至2016年3月在中国医科大学附属盛京医院胸外科行肺叶切除术、系统淋巴结清扫术,术后病理证实为Ⅰ-Ⅲ期肺癌患者的临床资料。按照是否发生胸部并发症分为两组,分析比较两组患者的特征。对两组患者的一般资料、术前合并症、术前检查、手术情况等进行单因素分析,对有显著性差异的结果纳入二元Logistic回归方程进行多因素分析。结果:对单因素分析具有统计学差异的指标进行二元Logistic回归多因素分析,结果显示患者年龄(OR=1.053,95%CI:1.02~1.088,P=0.002)、手术部位(P=0.024)、手术方式(OR=2.257,95%CI:1.287~3.957,P=0.005)及手术持续时间(OR=1.007,95%CI:1.002~1.011,P=0.004)与无并发症组相比具有统计学差异(P<0.05)。结论:患者年龄、手术部位、手术方式及手术持续时间是肺癌术后发生胸部并发症的危险因素。Objective： To explore the risk factors of postoperative thoracic complications in patients with lung cancer,and to provide more evidence of evidence-based medicine.Methods： To retrospectively analyze the clinical data of patients from June 2014 to March 2016 in Shengjing Hospital of China Medical University with lobectomy and lymph node dissection,postoperative pathology for stages I-III lung cancer.Two groups were analyzed and compared according to the occurrence of chest complications.A single factor analysis was performed by analyzing the general information,preoperative complications,preoperative examination and the operation process,then took all the factors with significant differences into Logistic regression for multifactor analysis.Results： After Logistic regression multivariate analysis,age（OR = 1.053,95% CI： 1.02 - 1.088,P = 0.002）,surgical site（P = 0.0 2 4）,operation method（OR= 2.257,95% CI： 1.287 - 3.957,P = 0.005） and duration of operation（OR = 1.0 0 7,9 5 % CI ： 1.002 - 1.011,P= 0.004） have the statistical significance,compared with the no complication group（p〈0.05）.Conclusion： The age of patients,surgical site,surgical methods and duration are the risk factors of chest complications after lung cancer surgery.

关 键 词：肺癌根治术 胸部并发症 危险因素 

分 类 号：R734.2[医药卫生—肿瘤]