潮汕贲门癌高发区575例贲门病变分析  

Analysis of 575 cases of gastric cardia pathological changes in Chaoshan gastric cardia cancer high risk area

作　　者：陈广灿[1] 刘淑慧[2] 洪良利[3] Chen Guangcan Liu Shuhui Hong Liangli(Department of Gastrointestinal Surgery, the First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China Department of Pathology, the First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China Pathological Staff Room, Shantou University Medical College ,Shantou, Guangdong 515041, China)

机构地区：[1]汕头大学医学院第一附属医院胃肠外科,广东省汕头515041 [2]汕头大学医学院病理教研室,广东省汕头515041 [3]汕头大学医学院第一附属医院病理科,广东省汕头515041

出　　处：《中国基层医药》2017年第6期801-804,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：广东省自然科学基金资助项目（2014A030310139）;广东省医学科研基金资助项目（B2015110）

摘　　要：目的：观察汕头大学医学院第一附属医院575例贲门病变就诊患者的临床特征，初步了解潮汕贲门癌高发区贲门病变的发病情况。方法根据汕头大学医学院第一附属医院2007-2011年贲门病变患者内镜或手术病理诊断记录，分析就诊患者的人数、性别、年龄、病变诊断等。结果在该医院收治的575例各类贲门病变患者中，慢性炎症、低级别上皮内瘤变、高级别上皮内瘤变和贲门癌的患者人数分别占16．34％、3．3％、2．26％和78．09％，贲门癌患者例数最多。趋势χ^2检验结果显示，贲门癌患者的比例随着年龄增大逐渐升高（P ＝0．000）。贲门病变患者中男性明显多于女性，其中贲门癌患者男∶女为4．76∶1。结论汕头大学医学院第一附属医院就诊的贲门病变患者多为中老年男性人群，且以贲门癌患者人数最多，男性贲门癌患者明显多于女性。Objective To observe the clinical features of 575 patients with cardiac diseases from the First Affiliated Hospital of Shantou University Medical College,and to get a preliminary understanding of the incidence of cardia cancer in high incidence area of Chaoshan cardia lesions.Methods Recorded the clinical data of the patients with pathological changes of gastric cardia diagnosed in the First Affiliated Hospital of Shantou University Medical College from 2007 to 2011.Analyzed the distributions of these patients by sex,age and pathological changes.Results There were 575 cases with all kinds of pathological changes of gastric cardia enrolled in this hospital,including 16.34% of chronic inflammation,3.3% of low grade intraepithelial neoplasia,2.26% of high grade intraepithelial neoplasia and 78.09% of gastric cardia cancer.Most patients were gastric cardia cancer.Trend χ^2 test results showed that the numbers of gastric cardia cancer patients increased with age（P =0.000）.The prevalence of pathological changes of gastric cardia in males was obviously higher than that in females.In gastric cardia cancer the ratio of male to female was 4.76∶1.Conclusion Most of the patients with gastric cardia pathological changes admitted in the First Affiliated Hospital of Shantou University Medical College are middle -aged and elderly men,and gastric cardia cancer is common with a higher frequency in males than that in females.

关 键 词：贲门 炎症 肿瘤 流行病学研究特征(主题) 

分 类 号：R735.2[医药卫生—肿瘤]