血栓通联合吡拉西坦治疗老年性脑梗死后遗症的临床效果评价  

Evaluation on clinical effect of Xueshuantong combined with piracetam in the treatment of senile cerebral infarction sequelae

作　　者：王涛[1] WANG Tao(Department of Neurology, Jiangsu Province Wuxi City People＇s Hospital, Wuxi 214043, China)

机构地区：[1]江苏省无锡市人民医院神经内科,214043

出　　处：《中国实用医药》2017年第3期95-97,共3页China Practical Medicine

摘　　要：目的研究并探讨血栓通联合吡拉西坦治疗老年性脑梗死后遗症的临床疗效。方法 120例老年性脑梗死后遗症患者作为研究对象,采取抛掷硬币法将患者分为对照组及观察组,各60例。对照组给予吡拉西坦治疗,观察组给予吡拉西坦+血栓通治疗。对比两组患者的临床疗效、美国国立卫生院脑卒中量表(NIHSS)评分、Barthel指数。结果观察组总有效率(95.00%)明显高于对照组(81.67%),差异具有统计学意义(χ~2=5.175,P<0.05)。治疗前,两组患者的NIHSS评分、Barthel指数对比,差异均无统计学意义(P>0.05);治疗后,两组NIHSS评分均低于本组治疗前、Barthel指数均高于本组治疗前,且观察组治疗后NIHSS评分、Barthel指数均优于对照组,差异均具有统计学意义(P<0.05)。结论在老年性脑梗死后遗症患者中,采用血栓通联合吡拉西坦联合治疗方案具有显著的临床疗效,可有效改善患者的神经功能,提高患者的日常生活活动能力。Objective To study and explore the clinical effect of Xueshuantong combined with piracetam in the treatment of senile cerebral infarction sequelae. Methods A total of 120 senile patients with cerebral infarction sequelae as study subjects were randomly divided into control group and observation group, with 60 cases in each group. The control group received piracetam for treatment, and the observation group received piracetam ＋ Xueshuantong for treatment. Comparison were made on clinical effect, National Institutes of Health stroke scale（NIHSS） score and Barthel index in two groups. Results The observation group had higher total effective rate（95.00%） than the control group（81.67%）, and the difference had statistical significance（χ^2=5.175, P〈0.05）. There were no statistically significant difference in NIHSS score and Barthel index before treatment between two groups（P〉0.05）. After treatment, both groups had lower NIHSS score than before treatment, and higher Barthel index than before treatment. The observation group had better NIHSS score and Barthel index after treatment than those of the control group. All their difference had statistical significance（P〈0.05）. Conclusion Implement of Xueshuantong and piracetam shows significant clinical effect in the treatment of senile cerebral infarction sequelae, which can effectively improve the nerve function and increase activity of daily living in patients.

关 键 词：脑梗死后遗症 血栓通 吡拉西坦 

分 类 号：R743.33[医药卫生—神经病学与精神病学]