超声诊断并随访肾上腺神经母细胞瘤自然退化1例  

An adrenal neuroblastoma regression diagnosed and followed by ultrasound:a case report

作　　者：田超[1] 陈列[1] 朱才义[1] 

机构地区：[1]中南大学湘雅医学院附属海口医院超声科,海口570000

出　　处：《中南大学学报（医学版）》2017年第2期233-235,共3页Journal of Central South University ：Medical Science

摘　　要：神经母细胞瘤是一种交感神经系统的胚胎性肿瘤,由神经嵴的交感神经节细胞发展而来。中南大学湘雅医学院附属海口医院收治一名9 d患儿,经穿刺活检确诊为肾上腺神经母细胞瘤伴肝转移。在未接受任何治疗的情况下,持续超声观察随访6年,发现患儿肾上腺及肝内占位逐渐缩小直至消失,患儿自然痊愈。部分恶性肿瘤可能发生自然退化,其中以神经母细胞瘤最为常见,观察并研究自然退化现象对肿瘤治疗具有重要的意义。Neuroblastoma is an embryonal tumor of the sympathetic nervous system, arising during fetal or early post-natal life from sympathetic cells derived from the neural crest. A 9-day-old boy was diagnosed as adrenal neuroblastoma with liver metastasis by biopsy. After 6 years of follow-up with ultrasound observation, the boy presents a process of spontaneous recovery without any special treatment. Spontaneous regression of cancer is defined as the decrease in size or disappearance of a primary tumor or metastatic disease without therapeutic intervention. Neuroblastoma is known to show the highest rate of spontaneous regression among malignant tumors. A better understanding of the mechanisms for spontaneous regression might help to identify optimal therapeutic approaches for patients with these tumors.

关 键 词：神经母细胞瘤 自然退化 超声 肝转移 肾上腺 

分 类 号：R739.4[医药卫生—肿瘤] R445.1[医药卫生—临床医学]