肝脏转移瘤相关治疗方案及其预后  

Treatment options and prognosis of malignant tumors with hepatic metastasis

作　　者：荀静宇 孙晨[1] 李福军[1] 吴德全[1] 

机构地区：[1]哈尔滨医科大学附属第二医院普通外科六病房,哈尔滨150086

出　　处：《中国普外基础与临床杂志》2017年第3期386-390,共5页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的总结恶性肿瘤肝转移相关治疗方案及其预后。方法回顾性收集近些年国内外关于恶性肿瘤肝转移的相关文献,按照不同的治疗方案分别进行总结:总结不同治疗方案下患者的临床治疗效果、生存期等。结果随着影像学和外科手术技术的发展和对恶性肿瘤认识的深化,许多恶性肿瘤的肝脏转移可被发现和治疗,从根本上也改变了以往对于恶性肿瘤肝转移治疗的观念,尤其是对原发病灶和肝脏转移瘤的根治性手术切除,是目前恶性肿瘤肝转移患者获得临床治愈的最佳方法。除了手术治疗外,恶性肿瘤肝转移的治疗方法还包括射频消融术(radio frequency ablation,RFA)、经肝动脉栓塞化疗(transarterial chemoembolization,TACE)、化疗、125I粒子植入治疗、冷冻治疗、立体定向放射治疗(stereotactic body radiation therapy,SBRT)、经皮激光热疗(laserinduced interstitial thermotherapy,LITT)、基因靶向治疗等。结论现在对于恶性肿瘤肝转移多采取积极的手术治疗和(或)个体化的综合治疗,这对于延长患者的生存期和改善患者的预后均起到了积极的作用。Objective To summarize the treatment and prognosis of malignant tumors with hepatic metastasis. Methods Review and analysis of recent relevant literatures at home and abroad of malignant tumors with liver metastasis, according to the different treatments were summarized. Evaluation of the patients＇ clinically curative effect and survival situation was performed under different treatments. Results With the development of imaging and surgical techniques, and deeply understanding of malignant tumor, many malignant tumors with liver metastasis could be found and treated, and previous concept of treatment for malignant tumors with liver metastasis was also fundamentally changed, and radical resection of the primary lesions and liver metastasis was the best way to get clinically curative effect for the patients with malignant tumors with liver metastasis. The treatments of malignant tumors with liver metastasis also included radio frequency ablation （RFA）, transarterial chemoembolization （TACE）, chemotherapy, ^125I seed implantation, cryotherapy, stereotactic body radiation therapy （SBRT）, laser-induced interstitial thermotherapy （LITT）, gene targeting therapy, and so on. Conclusion Now for malignant tumors with liver metastasis, positive surgery and （or） individualized comprehensive treatment are taken more often, and they play positive role to prolong the survival and improve the prognosis of malignant tumors patients with liver metastasis.

关 键 词：肝转移 恶性肿瘤 治疗 预后 

分 类 号：R735.7[医药卫生—肿瘤]