肝癌介入治疗对原发性肝癌中晚期患者的效果及肝功能的影响  

Effect of interventional treatment on curative efficacy and liver function of patients with middle and advanced primary hepatocellular carcinoma

作　　者：何伟[1] 赵许亚[1] 李俊祥[1] 曹葳[1] 

机构地区：[1]贵州省肿瘤医院介入科,贵州贵阳550004

出　　处：《实用临床医药杂志》2017年第3期71-74,共4页Journal of Clinical Medicine in Practice

基　　金：贵州省自然科学基金(29123)

摘　　要：目的探讨原发性肝癌中晚期患者经肝癌介入治疗后的效果及对肝功能的影响。方法选取本院接受治疗的50例原发性肝癌患者,采用肝癌介入治疗技术对其进行诊治,对比治疗后效果以及对其肝脏功能的影响。结果治疗2次后,患者的完全缓解率(58.00%)明显高于治疗1次后完全缓解率(30.00%),差异有统计学意义(P<0.05)。治疗后2年,患者的存活率(66.00%)与治疗后1年患者的存活率(78.00%)相比无显著差异(P>0.05)。介入治疗1 d后,患者ALT、TBIL与治疗前相比显著降低,白蛋白显著高于治疗前,AFP降低较慢,差异有统计学意义(P<0.05)。结论原发性肝癌中晚期患者经肝癌介入治疗后的效果显著,能够清除患者肿瘤病灶,改善其肝脏功能。Objective To analyze the intervention effect and the influence on liver function in patients with advanced primary hepatocellular carcinoma. Methods A total of 50 patients with primary hepatocellular carcinoma were treated with interventional therapy in our hospital. Treatment outcomes after treatment and the effect on liver function were compared. Results The complete remission rate after two times of treatment was 58.00% , which was obviously higher than 30.00% after one time treatment （ P 〈 0.05 ）. After two year of treatment, 2 year survival rate of patients was 66.00% ,which was significantly higher than 78.00% after 1 year treatment, but there was no significant difference （ P 〉 0.05 ）. After 1 day of interventional treatment, levels of ALT, TBIL were significantly decreased than intervention before, albumin level was significantly higher than the treatment before, AFP decreased slower, and the differences were statistically significant （P 〈 0.05 ）. Conclusion The interventional therapy can exert obvious effect in treatment of advanced primary hepatocellular carcinoma, clear cancer lesions, and improve patient＇s liver function.

关 键 词：原发性肝癌 肝癌介入治疗术 肝功能 

分 类 号：R735.7[医药卫生—肿瘤]