益生菌在特应性皮炎中的应用进展  

Probiotics for the treatment of atopic dermatitis

作　　者：孔雪[1] 毛世旺 张怀亮[1] Kong Xue Mao Shiwang Zhang Huailiang(Department of Integrated Traditional Chinese and Western Medicine, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing 210042, China)

机构地区：[1]中国医学科学院北京协和医学院皮肤病研究所中西医结合科,南京210042

出　　处：《国际皮肤性病学杂志》2017年第2期69-72,共4页International Journal of Dermatology and Venereology

摘　　要：特应性皮炎是一种慢性复发性皮肤病，大部分发生在婴儿和童年期。流行病学研究发现，在过去的30年中，许多国家特应性皮炎的患病率大幅度增加，皮肤屏障破坏、免疫功能异常、菌群改变是其发病的主要原因。益生菌是活的微生物，补充适当的数量对宿主产生益处，作为一个免疫调节剂，已证明其安全性，临床上可以治疗炎症性皮肤病，如特应性皮炎。Atopic dermatitis （AD） is a chronic recurrent skin disease, and mostly occurs during infancy and childhood. Epidemiologic studies have found that the prevalence of AD has been greatly increasing in many countries in the past 30 years. The occurrence of AD is mainly related to skin barrier impairment, abnormality of immune function and changes of bacterial flora. Probiotics are live microorganisms, and appropriate probiotic supplementation is beneficial to the host. As a kind of immune modulator, their safety has been proved. In clinic, probiotics can be used for the treatment of inflammatory skin diseases, such as AD.

关 键 词：皮炎 特应性 微生物群落 免疫调节 益生元 治疗应用 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]