胃复春联合四联疗法治疗H.pylori相关性慢性非萎缩性胃炎临床疗效观察  

Clinical efficacy of Weifuchun combined with quadruple therapy in treatment of chronic non-atrophic gastritis

作　　者：何孝明 黄宣[3] Xiao-Ming He Xuan Huang(Zhejiang Chinese Medical University, Hospital of integrated traditional Chinese and Western Medicine in Xiacheng District of Hangzhou City, Hangzhou 310000, Zhejiang Province, China Department of Gastroenterology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310000, Zhejiang Province, China)

机构地区：[1]浙江中医药大学 [2]杭州市下城区中西医结合医院,浙江省杭州市310000 [3]浙江中医药大学附属第一医院消化内科,浙江省杭州市310000

出　　处：《世界华人消化杂志》2017年第6期521-525,共5页World Chinese Journal of Digestology

基　　金：浙江省中医药科学研究基金资助项目;Nos.2016ZA089;2014ZB041~~

摘　　要：目的观察胃复春联合四联疗法对幽门螺杆菌(Helicobacter pylori,H.pylori)相关性慢性非萎缩性胃炎的治疗效果.目的选取196例H.pylori相关性慢性非萎缩性胃炎患者,随机分为治疗组(胃复春联合四联疗法)99例和对照组(四联疗法)97例,比较2组患者治疗后的临床症状和胃镜改善情况以及H.pylori根除率.结果治疗组患者症状总有效率、胃镜总有效率和H.pylori根除率均高于对照组(93.9%vs85.6%,91.9%vs 84.5%,92.9%vs 83.5%),疗效明显优于对照组,差异具有统计学意义(P<0.05).结论胃复春联合四联疗法治疗H.pylori相关性慢性非萎缩性胃炎疗效优于单纯四联疗法,可提高H.pylori根除率,值得在临床推广使用.AIM To observe the curative effect of Weifuchun combined with quadruple therapy for Helicobacter pylori（H.pylori）-related chronic non-atrophic gastritis.METHODS A total of 196 chronic non-atrophic gastritis patients who tested positive for H.pylori were randomly divided into either a control group（n= 97;quadruple therapy alone） or a treatment group（n = 99;Weifuchun combined with quadruple therapy）.The H.pylori eradication rates,gastroscopic and clinical curative effects were compared between the two groups.RESULTS The H.pylori eradication rate,gastroscopic and symptom total effective rates in the treatment group were 92.9%,91.9%and 93.9%,respectively,which were significantly higher than those in the control group（83.5%,84.5%and 85.6%,respectively;P〈0.05）.CONCLUSION The curative effect of Weifuchun combined with quadruple therapy is superior to quadruple therapy in the treatment of H.pylori related chronic non-atrophic gastritis,and it can effectively improve H.pylori eradication rate.

关 键 词：胃复春 四联疗法 幽门螺杆菌 慢性非萎缩性胃炎 

分 类 号：R573.32[医药卫生—消化系统]