壳聚糖-PEG-Ag纳米复合材料的制备及抗菌性能  

Study on the fabrication and antibacterial property of the chitosan-PEG-Ag nanocomposite

作　　者：宫雪[1] 魏铄蕴[1] 李全芳[1] 曾俊菱 王建荣[2] 

机构地区：[1]甘肃政法学院甘肃省证据科学技术研究与应用重点实验室,兰州730070 [2]甘肃省妇幼保健院,兰州730050

出　　处：《兰州大学学报（自然科学版）》2017年第1期139-142,共4页Journal of Lanzhou University(Natural Sciences)

基　　金：甘肃政法学院2015年度校级重点项目(GZFXZDLW010)

摘　　要：制备了Ag纳米粒子修饰的壳聚糖-PEG纳米复合材料,使用傅里叶红外光谱仪、X射线衍射仪和扫描电子显微镜对该复合纳米材料的物理、化学性质进行了表征和分析.使用纸片扩散法和光度法进行了体外抑菌实验,结果表明该复合纳米材料对大肠杆菌和金黄色葡萄球菌均具有很好的抑制生长作用,且属于广谱抑菌剂.Chitosan nanocomposites doped with silver nanoparticles were synthesized and the developed nanocomposites were characterized using Fourier transform infrared spectroscopy,X-ray diffraction and scanning electron microscope to understand their physico-chemical properties;tests for inhibiting bacteria growth were investigated by disk diffusion and turbidity method in vitro.The results of antibacterial experiment demonstrated that the nanocomposites had excellent antibacterial activity towards Escherichia coli and Staphylococcus aurous,classified as a broadly antibacterial agent.

关 键 词：纳米复合材料 抑菌活性 广谱抑菌剂 壳聚糖 

分 类 号：TB33[一般工业技术—材料科学与工程]