胃底腺息肉与结直肠肿瘤相关性  

Correlation between fundic gland polyps and colorectal neoplasms

作　　者：郝月茗 李佳[1] 刘婉琦[1] 孟祥伟[1] Yue-Ming Hao Jia Li Wan-Qi Liu Xiang-Wei Meng(Department of Gastrointestinal Medicine, the First Hospital of Jilin University, Changchun 130021, Jilin Province, China)

机构地区：[1]吉林大学第一医院胃肠内科,吉林省长春市130021

出　　处：《世界华人消化杂志》2017年第7期610-614,共5页World Chinese Journal of Digestology

摘　　要：目的探讨胃底腺息肉(fundic gland polyps,FGPs)与结直肠肿瘤的相关性.方法回顾性收集2013-05/2016-05所有在吉林大学第一医院同期行胃镜及肠镜检查的患者病历资料,分为FGPs组(243例)和对照组(486例).使用SPSS17.0软件进行统计分析,探讨FGPs和结直肠肿瘤的相关性.结果F G P s组结直肠肿瘤检出率高于对照组[19.8%(48/243)vs 8.8%(43/486)],其中结直肠癌的检出率差异无统计学意义(P=0.67),而结直肠腺瘤的检出率差异有统计学意义(P<0.001).通过对年龄、性别进行分层分析得出,女性及≥50岁的FGPs患者的结直肠肿瘤检出率明显高于对照组(P<0.001,0.001).进一步就不同部位的结直肠肿瘤分层分析显示,FGPs合并结直肠肿瘤的患者中,女性及≥50岁的,无论是在近端结肠还是远端结直肠,结直肠肿瘤检出率均高于对照组(P<0.05).结论患有FGPs尤其是女性及≥50岁的患者,合并近端结肠及远端结直肠肿瘤的风险增高,应尽早行肠镜检查.AIM To investigate the correlation between fundic gland polyps（FGPs） and colorectal neoplasms.METHODS Clinical data of patients who underwent both gastroduodenoscopy and colonoscopy during the period from May 2013 to May 2016 at the First Hospital of Jilin University were retrospectively analyzed.The patients were divided into either an FGPs group（243 cases）or a control group（n=486）.SPSS17.0 software was used for statistical analysis to assess the correlation between FGPs and colorectal neoplasms.RESULTS Colorectal neoplasms were detected in19.8%（48/243） of patients with FGPs,while only in 8.8%（43/486） of the control group.The incidence of colorectal cancer was not significantly different（P = 0.67）,while the incidence of colorectal adenoma was significantly different between the two groups（P〈0.001）.Stratified analysis showed that the incidence of colorectal neoplasms in the FGPs group was higher than in the control group in females and in patients aged more than 50years（P〈0.001 for both）.Stratified analysis of different parts of colorectal neoplasms suggested that the incidence of colorectal neoplasms in patients who were female or aged over 50 years in the FGPs group was significantly higher than that in the control group,regardless of the proximal colon,distal colon or rectum（P〈0.05）.CONCLUSION Patients with FGPs,especially females or those aged over 50,have a higher risk for colorectal neoplasms.Colonoscopy is necessary in this group of patients.

关 键 词：胃镜 肠镜 胃底腺息肉 结直肠肿瘤 

分 类 号：R735.34[医药卫生—肿瘤]