搅拌联合经导管直接溶栓治疗非肝硬化急性门静脉血栓的临床疗效  

Clinical Efficacy of Agitation Thrombolysis Combined with Catheter-Directed Thrombolysis for the Treatment of Non-Cirrhotic Acute Portal Vein Thrombosis

作　　者：王朝阳[1] 任建庄[1] 韩新巍[1] 张文广[1] 张庆辉[1] 陈鹏飞[1] 赵国瑞[1] WANG Zhaoyang REN Jianzhuang HAN Xinwei et al(Department of Interventional Radiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, P. R. Chin)

机构地区：[1]郑州大学第一附属医院介入科,450000

出　　处：《临床放射学杂志》2017年第2期276-279,共4页Journal of Clinical Radiology

摘　　要：目的探讨搅拌联合经导管直接溶栓治疗非肝硬化急性门静脉血栓的临床疗效。方法搜集5例非肝硬化急性门静脉血栓,经皮经肝或经颈静脉肝内穿刺门静脉,采用搅拌技术溶解血栓,后留置导管持续应用溶栓药物。术后随访门静脉通畅情况。结果 2例采用经颈静脉途径,3例采用经皮经肝途径,搅拌溶栓后门静脉血流明显较前通畅,经留置导管溶栓后门静脉再通均>90%,无严重并发症发生。随访8~21个月过程中,门静脉血流均通畅,无一例血栓复发。结论搅拌联合经导管直接溶栓治疗非肝硬化急性门静脉血栓安全有效,中期随访过程中能维持门静脉血流通畅。Objective To evaluate the clinical efficacy of agitation thrombolysis combined with catheter-directed thrombolysis（ CDT） for the treatment of non-cirrhotic acute portal vein thrombosis（ PVT）. Methods From March 2014 to September 2015,5 patients of non-cirrhotic acute PVT were treated by agitation thrombolysis combined with CDT. Clinical follow-up of portal vein patency was conducted. Results Portal veins were reached via a transjugular intrahepatic portosystemic（ TIP） approach in 2 patients,and percutanous transhepatic portal in 3 patients. The blood flow was evidently improved after agitation thrombolysis. The recanalization of PV was all more than 90% after catheter directed thrombolysis（ CDT） without any serious complications. PV remained patent during the follow-up of 8- 21 mo. None of the patients developed PVT again. Conclusion Agitation thrombolysis combined with CDT is safe and effective for the treatment of noncirrhotic acute PVT and can maintain the patency of the PV during median follow-up.

关 键 词：门静脉血栓 搅拌溶栓 经导管溶栓 非肝硬化 

分 类 号：R575[医药卫生—消化系统] R816.5[医药卫生—内科学]