低辐射剂量联合低剂量对比剂在甲状腺CT增强扫描中的应用  

Application of Low Radiation Dose Combined with Low-dose Contrast Agent in Thyroid CT Enhanced Scan

作　　者：梁坚豪[1] 朱新进[1] 杨侃荣[1] 刘杰[1] 谭志成[1] 钟金龄 LIANG Jianhao ZHU Xinjin YANG Kanrong LIU Jie TAN Zhicheng ZHONG Jinling(Department of Imaging, the Affiliated Foshan Hospital of Southern Medical University, the Second People＇s Hospital of Foshan, Foshan 528000, Chin)

机构地区：[1]南方医科大学附属佛山医院(佛山市第二人民医院)影像科,广东佛山528000

出　　处：《中国医学影像学杂志》2017年第2期105-108,共4页Chinese Journal of Medical Imaging

摘　　要：目的探讨低辐射剂量联合低剂量对比剂扫描技术在甲状腺CT增强扫描中的可行性,以降低受检者的辐射危害及对比剂对甲状腺的影响。资料与方法前瞻性将120例行甲状腺CT增强扫描的患者随机分为4组(每组30例),A组:120 kV,180 mA,对比剂用量1.2 ml/kg;B组:120 kV,180 mA,对比剂用量1.0 ml/kg;C组:100 kV,100 mA,对比剂用量1.2 ml/kg;D组:100 kV,100 mA,对比剂用量1.0 ml/kg。测量甲状腺CT值、背景信号和背景噪声,计算信噪比(SNR)及对比信噪比(CNR),记录患者的CT容积剂量指数(CTDIvol)、剂量长度乘积(DLP),并计算有效辐射剂量(ED),由2名放射科医师对图像质量评分并对上述参数进行统计学分析。结果 4组图像的甲状腺CT值、背景信号及背景噪声、CTDIvol、DLP、ED差异有统计学意义(P<0.05),SNR、CNR及图像质量评分差异无统计学意义(P>0.05)。结论低辐射剂量联合低剂量对比剂在甲状腺CT增强扫描中既能保证图像质量又能显著降低辐射剂量及对比剂用量,减少辐射危害及对比剂不良反应。Purpose To explore the feasibility of low radiation dose combined with lowdose contrast agent in thyroid CT enhanced scan and investigate the benefit of reducing radiation hazard and contrast agent damage to thyroid. Materials and Methods 120 patients assigned for thyroid enhanced CT scan were prospectively and randomly divided into four groups（each group was 30 patients）. Group A： radiation dose 120 kV, 180 mA, contrast agent dose 1.2 ml/kg; group B： radiation dose 120 kV, 180 mA, contrast agent dose 1.0 ml/kg; group C： radiation dose 100 kV, 100 mA, contrast agent dose 1.2 ml/kg; group D： radiation dose 100 kV, 100 mA, contrast agent dose 1.0 ml/kg. CT values, background sign, background noise of thyroid were measured; signal to noise ratio（SNR） and contrast to noise ratio（CNR） were calculated; CT dose index of volume（CTDIvol）, dose length product（DLP）, and the effective dose（ED） were recorded and calculated. The image quality was evaluated and the data was statistically analyzed by two radiologists. Results CT values, background sign and background noise of thyroid, as well as CTDIvol, DLP, ED among four groups were statistical significant（P〈0.05）; there was no significant difference in SNR, CNR and image quality scores among four groups（P〈0.05）. Conclusion It is beneficial of reducing radiation hazard and side-effect of contrast agent from low radiation dose combined with low-dose contrast agent under the condition of ensuring diagnostic image quality.

关 键 词：甲状腺疾病 体层摄影术 螺旋计算机 图像增强 辐射剂量 造影剂 

分 类 号：R445.1[医药卫生—影像医学与核医学]