新疆地区907例甲状腺癌回顾性分析  

A retrospective study of 907 thyroid carcinoma cases in Xinjiang

作　　者：马琦[1] 希林古丽·吾守尔 五且昆·吐尔逊[2] 夏米西努尔·伊力克[2] 

机构地区：[1]新疆医科大学第一附属医院临床医学研究院、新疆代谢性疾病重点实验室,新疆乌鲁木齐830054 [2]新疆医科大学基础医学院生物教研室,新疆乌鲁木齐830011

出　　处：《癌变．畸变．突变》2017年第2期143-145,150,共4页Carcinogenesis,Teratogenesis & Mutagenesis

基　　金：国家自然科学基金(30860275)

摘　　要：目的:探讨新疆地区人群甲状腺癌的发病特点。方法:收集新疆医科大学第一附属医院2003年1月—2013年12月甲状腺癌患者病例资料907例,用SPSS 22.0及Microsoft Excel 2007软件分析新疆地区人群甲状腺癌的发病趋势及性别、年龄和族别差异。分2析方法采用χ检验,检验水准α=0.05。结果:2003—2013年间,甲状腺癌的构成比呈上升趋势;甲状腺癌的病理类型主要为乳头状癌(90.96%);患者男女人数比例1∶2.88,其构成比具有性别差异(P<0.05),男女发病年龄高峰均为40~49岁,女性病例增加程度高于男性;甲状腺癌的组织类型在汉族与维吾尔族间分布不同(P<0.05),乳头状癌在汉族患者中的比例(93.77%)高于维吾尔族(83%)。结论:过去10年当中该院收治甲状腺癌患者逐年增多,女性患者增加人数多于男性,男、女性甲状腺癌的高发年龄均为40~49岁,乳头状癌是主要的病理类型,病理类型的分布在汉族和维吾尔族之间存在差异。OBJECTIVE：To study the clinical characteristics of thyroid cancer in Xinjiang.METHODS：We collected information of 907 cases from the archive and analyzed the difference among the morbidity trend, gender,age,and ethnic groups.RESULTS：The number of thyroid cancer patients had markedly increased year by year. Among the cancer,papillary thyroid cancer（90.96%）was the dominant type. Morbidity of thyroid cancer showed significant differences among various age ranges and gender （male to female ratio of 1/2.88）（P〈0.05）. However,both genders had the same age peak （40-49）. In this age group,cases increased in women over men. The types of thyroid cancer was different between Han and Uyghur （P〈0.05）,with the ratio of papillary thyroid cancer higher in Han than in Uyghur （93.77% and 83%,respectively）.CONCLUSION：The incidence of thyroid cancer had increased in the Xinjiang population over the last 10 years. The increase in female was higher than that in male. The peak age was 40-49. The main pathology type was papillary thyroid cancer which showed ethnic differences.

关 键 词：甲状腺癌 民族差异 新疆人群 流行病学 临床资料 

分 类 号：R736.1[医药卫生—肿瘤]