甲状腺结节钙化与甲状腺癌的关系  

Relationship between thyroid nodule calcification and thyroid cancer

作　　者：刘烺飚 韩承新[2] 舒清明[3] 徐薪[3] 贾元利[2] LIU Langbiao HAN Chengxin SHU Qingming XU Xin and JIA Yuanli(Department of General Surgery, Beijing Tongzhou Xinhua Hospital, Beijing 101100, China Department of General Surgery Department of Pathology, General Hospital of Chinese People＇s Armed Police Force, Beijing 100039, China)

机构地区：[1]北京市通州区新华医院普外科,101100 [2]武警总医院普通外科,北京100039 [3]武警总医院病理科,北京100039

出　　处：《武警医学》2017年第2期150-151,156,共3页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的探讨术前超声发现甲状腺结节钙化与甲状腺癌的关系。方法回顾性分析武警总医院2012-06至2012-08行甲状腺结节手术的患者,术前超声检查的甲状腺结节钙化类型,以及和术中、术后病理结果之间关系。结果 58例中,良性病变31例,甲状腺乳头状癌27例。术前超声甲状腺结节钙化检出率39.7%,术后病理的钙化检出率为38%,术中冷冻的钙化检出率为17.2%。良性病变钙化检出率为16.1%,良性病变微钙化检出率6.4%;甲状腺乳头状癌钙化发生率66.7%,其中微钙化发生率为51.9%。良性病变与恶性病变之间的钙化发生率、微钙化发生率比较,差异均有统计学意义(P<0.01)。良性病变的单个结节钙化发生率为20%,恶性病变的单个结节钙化发生率为61.1%,两者比较差异有统计学意义(P<0.01)。结论术前超声发现的甲状腺结节的微钙化与甲状腺癌的关系密切。Objective To evaluate the relationship between sonographic patterns of thyroid nodule calcification and thyroid cancer. Methods Fifty-eight patients who had undergone thyroid surgery in the General Hospital of Chinese People＇s Armed Police Force between June 2012 and August 2012 were retrospectively analyzed,with emphasis on benign and malignant thyroid nodular calcification in general and preoperative ultrasound examination of thyroid nodule calcification,postoperative pathologic results,and the relationships between preoperative ultrasonographic calcification and thyroid cancer in particular. Results Among the 58 cases,there were 31 cases of benign lesions and 27 cases of thyroid papillary carcinoma. The detection rate of preoperative ultrasound calcification was 39. 7%,the pathological calcification rate was 38%,and intraoperative frozen calcification rate was 17. 2%. The detection rate of benign calcification was 16. 1%,the incidence of microcalcification of benign lesions was 6. 4%,the incidence of calcification of thyroid papillary carcinoma was 66. 7%,and the incidence of microcalcification was 51. 9%. The differences of microcalcification between benign lesions and malignant lesions were statistically significant（ P〈0. 01）. The calcification incidence of the single benign nodular was 20%,and the calcification incidence of the single malignant nodular was 61. 1%,so where was significant difference between them（ P〈0. 01）. Conclusion Thyroid nodule microcalcification detected by ultrasound is closely related to thyroid cancer.

关 键 词：甲状腺结节 甲状腺癌 钙化 

分 类 号：R736.1[医药卫生—肿瘤]