Will cancer cells be defeated by sodium bicarbonate？  

作　　者：Hongtao Zhang 

机构地区：[1]Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia PA 19104, USA

出　　处：《Science China(Life Sciences)》2017年第3期326-328,共3页中国科学（生命科学英文版）

基　　金：supported by the Breast Cancer Research Foundation and the National Institutes of Health to Mark I.Greene (R01CA089481,R01CA149425);the Department of Defense Lung Cancer Research Program Idea Development Award grant to Sunil Singhal (W81XWH-15-1-0362)

摘　　要：Chao et al.reported an improved version of the transarterial chemoembolization（TACE）procedure for large hepatocellular carcinoma（HCC）,in which 5%sodium bicarbonate was infused into tumors to supplement chemotherapeutic agents.In a small randomized control trial,Chao et al.reported an improved version of the transarterial chemoembolization(TACE)procedure for large hepatocellular carcinoma(HCC),in which 5%sodium bicarbonate was infused into tumors to supplement chemotherapeutic agents.In a small randomized control trial,TACE combined with bicarbonate yielded a 100%objective response rate(ORR),a significant improvement from the 63.6%ORR in the TACE alone group(Chao et al.,2016).This optimized procedure is termed targeting-intratumorallactic-acidosis TACE(TILA-TACE),as the authors

关 键 词：碳酸氢钠 癌细胞 随机对照试验 化疗药物 HCC 肝动脉 小规模 

分 类 号：R730.5[医药卫生—肿瘤]