特发性视网膜前膜的临床分类及胶原测定  

Clinical classification and collagen measurement for idiopathic epiretinal membrane

作　　者：汪向利[1] 马建军[1] 

机构地区：[1]甘肃省人民医院眼科,中国甘肃省兰州市730000

出　　处：《国际眼科杂志》2017年第4期775-777,共3页International Eye Science

摘　　要：目的:通过对特发性视网膜前膜的两种胶原测定决定前膜类型。方法:对25例25眼特发性视网膜前膜依据眼底表现进行分类,包括玻璃体纸样黄斑反射膜(cellophane macular reflex membrane,CMRM)型和视网膜前黄斑纤维膜(preretinal macular fibrosis membrane,PMFM)型,并对手术获取的该25例25眼特发性视网膜前膜行免疫组织化学,测定组织中Ⅵ型及Ⅰ、Ⅱ型胶原,比较眼底检查与病理检查的符合率。结果:依据眼底表现将特发性视网膜前膜分CMRM型共10例10眼,PMFM型共15例15眼;对手术获取的标本行免疫组化结果:Ⅵ型胶原纤维为主者16例16眼,Ⅰ、Ⅱ型胶原为主者9例9眼。结论:特发性视网膜前膜类型应以病理特征为主。·AIM： To decide the type of the idiopathic epiretinal membrane by measuring collagens. ·METHODS：Totally 25 cases （25 eyes） were divided into cellophane macular reflex membrane （ CMRM ） and preretinal macular fibrosis membrane（ PMFM） by fundus manifestation. Then the specimens of peeled idiopathic epiretinal membranes were made immunohistochemistry and measured for the collagen of Ⅵ and Ⅰ and Ⅱ. The coincidence rate were tested between the fundus examination and pathological examination. ·RESULTS： The idiopathic epiretinal membranes were classified into 10 CMRM and 15 PMFM by fundus manifestation. The immunohistochemical specimens were classified into 16 Ⅵ collagens and 9Ⅰ or Ⅱ collagens. ·CONCLUSION： The pathological examination is the means of the type of the idiopathic epiretinal membranes.

关 键 词：特发性视网膜前膜 免疫组化 胶原 

分 类 号：R774.1[医药卫生—眼科]