皮脂腺痣并发基底细胞癌及管状乳头状大汗腺腺瘤  

Nevus sebaceous accompanied by basal cell carcinoma and tubulopapillary apocrine adenoma

作　　者：黄东北[1] 杨惠芳[1] 万春雷[1] 

机构地区：[1]赣南医学院第一附属医院皮肤科,江西赣州341000

出　　处：《临床皮肤科杂志》2017年第4期263-265,共3页Journal of Clinical Dermatology

摘　　要：报告1例皮脂腺痣并发基底细胞癌及管状乳头状大汗腺腺瘤。患者男,43岁。因右侧头部斑块43年就诊。皮肤科检查:右侧头部见淡黄色丘疹、结节及疣状斑块,质软,边界清楚,局部见数个大小不等黑色结节。皮损组织病理检查示(1)切片右侧:表皮角化过度伴角化不全,真皮浅、中层可见大小不等的肿瘤细胞团块,部分和表皮相连,肿瘤细胞团块由基底样细胞组成,肿瘤团块周边细胞呈栅栏状排列并可见收缩间隙;(2)切片左侧:表皮角化过度、棘层肥厚,乳头瘤样增生,真皮浅、中层可见增生的皮脂腺及以淋巴细胞为主的炎性细胞浸润,真皮深层见大汗腺分布,形成较多管腔样结构,管腔内见大汗腺呈乳头状突入管腔。A case of nevus sebaceous combined with basal cell carcinoma and tubulopapillary apocrine adcnoma is reported. A 43 year old man presented with a 43 year history of plaque on the right head. Clinical examination showed a yellow, well circumscribed and soft papule, node and plaque with a verrucous surface on the right head; part of them presented with several black nodes in differ- ent sizes. The histopathologic examination showed hyperkeratosis, parakeratosis. There were tumor clumps of different sizes which were composed of basaloid cells, some of them were connected with the epidermis. The cells surrounding the tumor clumps were in palisad- ing arrangement, and contraction gap was observed （the right side）. The other part of the skin lesion showed hyperkeratosis, acanthosis and papillomatoid proliferation of the epidermis, hyperplasia of the sebaceous glands and inflammatory cells infiltration in the dermis; The apocrine glands were located in the deep dermis and formed tubes, cells protruded into the tubes and formed the papillary appear- ance（the left side）.

关 键 词：痣 皮脂腺 基底细胞癌 管状乳头状大汗腺腺瘤 

分 类 号：R739.5[医药卫生—肿瘤]