超声乳化手术治疗高龄青光眼合并白内障患者的有效性与安全性分析  

The effectiveness and safety of phacoemulsification for the aged patients with glaucoma and cataract

作　　者：李科[1] 韩姬[1] 李雷[1] 郑振优[1] 

机构地区：[1]海南医学院附属医院眼科,海口570102

出　　处：《东南国防医药》2017年第1期5-7,共3页Military Medical Journal of Southeast China

基　　金：海南省自然科学基金项目(813233)

摘　　要：目的探讨超声乳化手术治疗高龄青光眼合并白内障患者时对于角膜内皮细胞和眼内压的影响。方法选取海南医学院附属医院自2013年8月至2014年8月间收治的高龄青光眼合并白内障患者70例(患眼70只)作为研究对象,所有患者均行超声乳化手术进行治疗,观察治疗前后患者的眼内压、角膜内皮细胞的完整性、并发症发生等情况,分析并发症发生的原因。结果手术治疗后30 d内,患者的眼内压与术前比较差异有统计学意义(P<0.05),30 d后差异不具有统计学意义(P>0.05);细胞密度(CD)指标在术后持续降低(P<0.05),细胞体积(AVE)和内皮细胞变异系数(CV)两项指标持续升高(P<0.05),角膜中央平均厚度(CCT)指标术后30 d与术前比较差异不具有统计学意义(P>0.05)。出现并发症15例,均为术后角膜水肿,并发症发生率为21.43%,影响因素为晶体核硬度、眼部手术史、基础性疾病等。结论使用超声乳化术治疗高龄青光眼合并白内障患者在短期内会影响患者的眼内压和角膜细胞的密度等,长远期来看影响较小。Objective To investigate the effectiveness and safety of phacoemulsification for the aged patients with glaucoma and cataract. Methods 70 cases（70 eyes） of patients were selected as the research object in our hospital from August 2013 to August. All patients were treated with phacoemulsification. The intraocular pressure and corneal endothelial cell integrity were observed in the patients. Results After surgical treatment,the intraocular pressure difference was significant（ P〈0. 05） in patients with 30 d,and the difference was not statistically significant（ P〈0. 05） after 30 d; After surgical treatment,the CD index were decreased（ P〈0. 05）,AVE and CV index were increased（ P〈0. 05）,and CCT index compared with preoperative was not statistically significant different（ P〈0. 05） after 30 d. The incidence rate of complications was 21. 43%,and the influence factors were the crystal nucleus hardness and the history of ocular surgery. Conclusion The use of phacoemulsification surgery in the treatment of elderly patients with glaucoma and cataract in the short term will have an impact on the intraocular pressure and corneal endothelial cells,but the impact is small in the long run.

关 键 词：高龄 青光眼合并白内障 超声乳化手术 眼内压 角膜内皮细胞 

分 类 号：R779.6[医药卫生—眼科]