经皮胆道覆膜支架置入联合疏肝利胆法治疗胆总管中下段MOJ临床疗效观察  

Observation on clinical effect of percutaneous biliary tract coated stent implant combined with Shuganlidan method for treating malignant obstructive jaundice in middle and lower part of common bile duct

作　　者：刘文导[1] 冯柳迁 孟凡喆[1] 常钢[1] 

机构地区：[1]广东省中医院介入科,广州510120

出　　处：《检验医学与临床》2017年第6期794-796,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨经皮胆道覆膜支架置入联合疏肝利胆法和单纯裸支架置入治疗胆总管中下段恶性梗阻性黄疸(MOJ)的临床疗效。方法回顾分析该院2009-2015年收治的53例MOJ患者,分为覆膜支架+疏肝利胆法组25例(治疗组),单纯裸支架组28例(对照组)。对两组患者支架通畅时间、生存时间、并发症发生率进行分析和比较。结果治疗组和对照组的术后中位支架通畅时间分别为346d和181d,差异有统计学意义(P<0.05),中位生存时间分别为362d和168d,差异有统计学意义(P<0.05),术后并发症发生率分别为16.0%和10.7%,差异无统计学意义(P>0.05)。结论覆膜支架置入联合疏肝利胆法治疗胆总管中下段梗阻,患者术后支架远期通畅率高,生存质量提高,生存时间延长,而且并发症少,安全有效,值得临床推广。Objective To investigate the clinical efficacy of percutaneous biliary tract coated stent implant combined with Shuganlidan method in the treatment of malignant obstructive jaundice（MOJ）in the middle and lower part of the common bile duct.Methods Fifty-three patients with MOJ in our hospital during 2009-2015 were retrospectively analyzed.Among them,25 cases were treated with the covered stent＋Shuganlidan method（treatment group）and 28 cases received the simple bare stent（control group）.The stent patency time,survival time and occurrence rate of complications were analyzed and compared between the two groups.Results The median postoperative stent patency time in the two groups were 346 dand 181drespectively,the difference was statistically significant（P〈0.05）;median survival time was 362 dand 168drespectively,the difference was statistically significant（P〈0.05）;the occurrence rate of postoperative complications were 16.0% and 10.7%without statistical difference between them（P〉0.05）.Conclusion The coated stent implant combined with Shuganlidan method for treating obstruction in the middle and lower part of the common bile duct has high long-term stent patency rate,increases the survival quality,extends the survival time with less complications,safety and effectiveness,which is worth clinical promotion.

关 键 词：恶性梗阻性黄疸 覆膜支架 裸支架 疏肝利胆 

分 类 号：R735.1[医药卫生—肿瘤]