声触诊组织量化成像技术对颈部恶性淋巴瘤与反应性增生淋巴结的鉴别诊断价值  

Value of virtual touch tissue imaging quantification in differentiating cervical lymphomas and reactive hyperplasia lymph nodes

作　　者：奚佳颖[1] 赵颖燕[1] 赵宝珍[1] 熊文峰[1] 蒋栋[1] 杨力[1] 金修才[1] XI Jiaying ZHAO Yingyan ZHAO Baozhen XIONG Wenfeng JIANG Dong YANG Li JIN Xiucai(Department of Ultrasound, Changhai Hospital of Second Military Medical University, Shanghai 200433, Chin)

机构地区：[1]第二军医大学附属长海医院超声科,上海市200433

出　　处：《临床超声医学杂志》2017年第3期159-163,共5页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨声触诊组织量化成像(VTIQ)技术对颈部恶性淋巴瘤与反应性增生淋巴结的鉴别诊断价值。方法回顾性分析45枚颈部恶性淋巴瘤的常规超声及VTIQ图像资料,并选择48枚颈部反应性增生淋巴结作对照,比较分析两者二维超声图像特征及彩色多普勒淋巴门血管模式,并测量其剪切波速度(SWV),以病理诊断结果为金标准,比较颈部恶性淋巴瘤与反应性增生淋巴结SWV之间的差异;绘制受试者工作特征(ROC)曲线,评价VTIQ鉴别颈部恶性淋巴瘤与反应性增生淋巴结的价值。结果恶性淋巴瘤SWV值为(3.37±0.93)m/s,反应性增生淋巴结SWV值为(2.20±0.49)m/s,二者比较差异有统计学意义(t=11.498,P=0.001)。构建SWV预测颈部恶性淋巴瘤的ROC曲线图,SWV值为2.54 m/s时是鉴别颈部恶性淋巴瘤与反应性增生淋巴结的诊断最佳界点,曲线下面积为0.904。VTIQ鉴别诊断颈部恶性淋巴瘤与反应性增生淋巴结的准确率88.2%,敏感性88.9%,特异性87.5%,阳性预测值87.0%,阴性预测值89.4%,优势比56。结论 VTIQ技术对鉴别颈部恶性淋巴瘤与反应性增生淋巴结有较好的应用价值。Objective To investigate the value of virtual touch tissue imaging quantification （VTIQ） in differentiating lymphomas and reactive hyperplasia lymph node. Methods The sonograms of conventional ultrasound and VTIQ examinations of 45 lymphomas and 48 reactive hyperplasia lymph nodes were retrospectively analyzed and compared. The two-dimensional ultrasound characteristics and the blood mode of the hilum on CDFI were observed.Shear wave velocities（ SWVs ） of lymphomas and reactive hyperplasia lymph nodes were measured. Taking pathologic results as the gold standred,the difference of SWVs between the lymphomas and reactive hyperplasia lymph nodes was compared. The receiver operating characteristic （ ROC ） curve was used to assess the value of VTIQ in differentiating lymphomas and reactive hyperplasia lymph nodes. Results SWV were （3.37±0.93）m/s for lymphomas and （2.20±0.49）m/s for nonspecific reactive lymph nodes（t=1 1.498,P=0.001 ）. The receiver operating characteristic（ ROC ） curve of SWVs in predicting lymphomas was drawn. The AUC was 0.904 and the SWV cut-off value was 2.54 m/s, the accuracy was 88.2%, the sensitivity was 88.9%, the specificity was 87.5%, the positive predictive value was 87.0% ,the negative predictive value was 89.4% ,and the odds ratio was 56. Conclusion VTIQ is valuable in differentiating cervical lymphomas and reactive hyperplasia lymph nodes.

关 键 词：声触诊组织量化成像 剪切波速度 淋巴结 颈部 良恶性 

分 类 号：R733.4[医药卫生—肿瘤] R445.1[医药卫生—临床医学]