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作 者:朱冉[1]
机构地区:[1]南阳医学高等专科学校,473004
出 处:《中国实用医药》2017年第4期30-32,共3页China Practical Medicine
基 金:南阳市2015年科技发展计划项目(项目编号:KJGG19)
摘 要:目的探讨消化系统恶性肿瘤合并急性脑梗死的临床特征,以提高医生对本病的认识,减少误诊率。方法 34例消化系统恶性肿瘤合并急性脑梗死患者作为肿瘤组,34例单纯性急性脑梗死患者作为非肿瘤组,收集两组临床资料并进行统计分析。结果两组患者年龄、性别比较差异无统计学意义(P>0.05)。两组高血压例数(10例VS 23例)及无危险因素例数(9例VS2例)比较差异有统计学意义(P<0.05);两组卒中史、糖尿病、心脏病、酗酒史、吸烟史例数比较差异无统计学意义(P>0.05)。两组血红蛋白(HGB)、血小板(PLT)、同型半胱氨酸(Hcy)水平比较差异具有统计学意义(P<0.05);两组血糖(BS)、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、纤维蛋白原(FIB)水平比较差异无统计学意义(P>0.05)。两组脑梗死灶分布比较差异具有统计学意义(P<0.05);两组脑梗死类型比较差异无统计学意义(P>0.05)。结论消化系统恶性肿瘤合并急性脑梗死与单纯性急性脑梗死发病的危险因素有所不同;合并消化系统恶性肿瘤患者HGB、PLT、TG、TC、LDL-C水平较低,常合并高同型半胱氨酸血症,病灶多为皮层梗死分布于单侧大脑半球。Objective Toexplore the clinical features of digestive system malignancy complicated with acute cerebral infarction, so as to improve the doctors knowledge of this disease and reduce the misdiagnosis rate. Methods There were 34 digestive system malignancy complicated with acute cerebral infarction patients as tumor group, and 34 simple acute cerebral infarction patients as non tumor group. Clinical data in two groups was collected and analyzed. Results There was no statistically significant difference in age and gender between two groups (P〉0.05). Both groups had statistically significant difference in hypertension cases (10 cases VS 23 cases) and no risk factor cases (9 cases VS 2 cases) between two groups (P〈0.05). There were no statistically significant difference in cases of stroke history, diabetes, heart disease, alcoholism history and smoking history between two groups (P〉O.05). Both groups had statistically significant difference in hemoglobin (HGB), platelet (PLT), homoeysteine (Hcy) levels between two groups (P〈0.05). There were no statistically significant difference in blood sugar (BS), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), fibrinogen (FIB) level between two groups (P〉0.05). Both groups had statistically significant difference in cerebral infarcts distribution between two groups (P〈0.05), had no statistically significant difference in cerebral infarction types between two groups (P〉0.05). Conclusion The risk factors are different between digestive system malignancy complicated with acute cerebral infarction and simply cerebral infarction. Patient complicated with digestive system malignancy has low level of tIGB, PLT, TG, TC, LDL-C, and often complicated with hyperhomocysteinemia, and mostly lesions are cortical infarction distributed in one cerebral hemisphere,
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