武夷岩茶复方颗粒剂对糖尿病大鼠的降血糖作用  

Experimental Study on Hypoglycemic Effect of Wuyi Compound Granule on Diabetic Rats

作　　者：安品弟 蒋慧颖[1] 马玉仙[1] 曾文治[1] 褚克丹[2] 杨江帆[1] 

机构地区：[1]福建农林大学园艺学院/中国乌龙茶协同创新中心,福建福州350002 [2]福建中医药大学药学院,福建福州350002

出　　处：《河南科技大学学报（医学版）》2017年第1期14-17,共4页Journal of Henan University of Science & Technology:Medical Science

基　　金：福建省"2011协同创新中心"中国乌龙茶产业协同创新中心专项(闽教科[2015]75号)

摘　　要：目的研究武夷岩茶复方颗粒剂对STZ糖尿病大鼠的影响。方法通过对Wistar大鼠进行腹腔注射链脲佐菌素(STZ)来建立糖尿病大鼠模型,对高血糖造模大鼠灌胃武夷岩茶或不同剂量的武夷岩茶复方颗粒剂,于给药30 d测量各组大鼠的空腹血糖值与糖耐量。结果武夷岩茶与武夷岩茶复方颗粒剂都能够控制STZ糖尿病大鼠血糖的提升以及改善大鼠糖耐量,其中,武夷岩茶复方颗粒剂的降血糖效果更好。结论本方法所制的武夷岩茶复方颗粒剂对糖尿病大鼠具有降血糖功效。Objective To study the effect of Wuyi compound granules on streptozotocin（ STZ） rats.Methods The diabetic rat model was established by intraperitoneal injection of STZ to Wistar. The hyperglycemic rats was intragastrical administration of Wuyi rock tea and Wuyi compound granules with different doses,and the blood glucose and glucose tolerance in rats were measured after 30 d. Results The results show that both the Wuyi rock tea or Wuyi compound granules can control the increase of STZ diabetic rats blood glucose and improve the glucose tolerance in rats,and the hypoglycemic effect of compound granule of Wuyi rock tea was better. Conclusion Wuyi compound granules made by the method have a hypoglycemic effect on diabetic rat.

关 键 词：糖尿病大鼠 链脲佐菌素(STZ) 武夷岩茶 武夷岩茶复方颗粒剂 

分 类 号：R587.1[医药卫生—内分泌]