“流空区”法诊断动脉粥样硬化准确性的比较研究  

The comparative study on veracity of flow-empty area method in the diagnosis of atherosclerosis

作　　者：于冬[1] 刘吉良[1] 李韶平[2] 曾玲[1] 

机构地区：[1]冀中能源峰峰集团有限公司总医院超声科,河北邯郸056200 [2]冀中能源峰峰集团有限公司总医院放射科,河北邯郸056200

出　　处：《医学影像学杂志》2017年第3期454-457,共4页Journal of Medical Imaging

基　　金：河北省医学科学研究重点课题计划(编号:20150825)

摘　　要：目的评价"流空区"法诊断动脉粥样硬化的价值。方法搜集2016年1月~2016年9月来我院进行颈动脉检查235例男性受检者的临床资料,观测颈动脉内是否出现"流空区"、颈动脉中膜-内膜厚度(CIMT)、肱动脉收缩压(Ps)、舒张压(Pd)、压力差(△P)、是否检出动脉粥样硬化斑块、计算压力应变弹力系数(Eρ)、硬化系数β。以CIMT增厚为诊断金标准,绘制ROC曲线,评价动脉内"流空区"法对诊断动脉粥样硬化的诊断价值。结果 ROC曲线显示"流空区"、Eρ、硬化系数β、年龄、△P、是否有动脉粥样硬化斑块检出六种方法诊断动脉粥样硬化的诊断准确性(曲线下面积分别为0.929、0.819、0.818、0.681、0.674、0.576);敏感度(95.03%、72.38%、72.93%、60.22%、53.04%、22.65%)、特异度(90.74%、87.04%、87.04%、46.30%、81.48%、92.59%)、误诊率(9.26%、12.96%、12.96%、53.70%、18.52%、7.41%)、漏诊率(4.97%、27.62%、27.07%、39.78%、46.96%、77.35%)。结论依据"流空区"法判断动脉粥样硬化的准确性较高。Objective To evaluate the value of flow-empty area method in the diagnosis of atherosclerosis. Methods The clinical data of 235 male participants, who were referred to our hospital for the examination of carotid, were collected in Hebei Jizhong Engery Fengfeng Group Co. General Hospital from January 2016 to September 2016. We observed whether the carotid ap- peared empty area, carotid intima-media thickness （CIMT） , the systolic pressure （Ps） , diastolic pressure （Pd） of brachial ar- tery, the pressure differential （△ P）, whether there was atherosclerosis plaque, and then, calculated the pressure strain elastic modulus （Ep） , and stiffness parameter β. Taking carotid thickness as diagnostic standard, we drew the receiver operating charac- teristic curve, evaluated the diagnostic value of artery flew-empty area exist in diagnosis of atherosclerosis. Results ROC showed that six parameters,i, e. , the flow-empty area, Ep, hardening coefficient, age, △P, whether existence of atherosclerosis plaque, were useful for the judgment of the accuracy in diagnosis of atherosclerosis. （ The area under the curve was 0. 929, 0. 819, 0. 818,0. 681,0. 674, 0. 576）. The sensitivity was 95.03%, 72.38%, 72.93%, 60.22%, 53.04%, 22.65%, the specifici- ty was 95.03%, 72.38% , 72.93% , 60.22%, 53.04% , 22.65% , the misdiagnosis rate was 9.26% , 12.96%, 12.96%, 53.70%, 18.52%, 7.41% and the missed diagnosis rate was 4.97% , 27.62% , 27.07%, 39.78% , 46.96%, 77.35%, re- spectively. Conclusion The accuracy is higher on the basis of flow-empty area method in diagnosis of atheroselerosis.

关 键 词：多普勒能量图M型分析 ROC曲线 动脉粥样硬化 流空区 超声检查 

分 类 号：R743.1[医药卫生—神经病学与精神病学] R445.1[医药卫生—临床医学]