阑尾恶性肿瘤13例临床病理分析  

Clinicopathological analysis of 13 cases of appendiceal malignant tumor

作　　者：李芝清 范乘龙 

机构地区：[1]浙江省绍兴市中心医院病理科,浙江绍兴312030

出　　处：《中国现代医生》2017年第5期101-104,F0003,共5页China Modern Doctor

摘　　要：目的探讨阑尾恶性肿瘤的临床特征及病理特点。方法回顾性分析绍兴市中心医院2009年1月-2016年6月间13例阑尾恶性肿瘤的临床及病理资料。结果 13例均有右下腹疼痛,9例白细胞计数大于10x104/L.12例体温低于37.51。原发性恶性肿瘤8例,为神经内分泌肿瘤1级(其中杯状细胞类癌1例);转移性恶性肿瘤5例,其中神经内分泌癌1例,腺癌4例。4例来源于结肠,1例来源于胃。结论阑尾恶性肿瘤缺乏特异性的临床症状及体征,术前诊断较困难。对白细胞升高无发热的患者,不能以急慢性阑尾炎解释,警惕阑尾炎与肿瘤并存,对老年患者还要排除转移可能,确诊需要依靠病理学及免疫组化检查。Objective To investigate the clinical features and pathological features of appendiceal malignant tumors. Methods The clinical and pathological data of 13 cases of appendiceal malignant tumors in Shaoxing Central Hospital from January 2009 to June 2016 were analyzed retrospectively. Results There were 13 cases who had right lower quad- rant pain, 9 cases of white blood cell count greater than 10×10^9/L, and 12 cases of body temperature below 37.5℃. 8 cases had primary malignant tumors and were neuroendocrine tumor grade 1 （including 1 case of goblet cell carcinoid）. 5 cases had metastatic malignancy, including 1 case of neuroendocrine cancer and 4 cases of adenocarcinoma. 4 cases were from the colon, and 1 case was from the stomach. Conclusion Appendiceal malignancy lacks specific clinical symptoms and signs, and its preoperative diagnosis is difficult. Patients who have elevated white blood cells without fever and can not be explained by acute and chronic appendicitis, should be watch out for appendicitis and tumor co- existence. The possibility of metastais also need to be ruled out for the elderly patients, and the diagnosis need to rely on pathology and immunohistochemistry examination.

关 键 词：阑尾肿瘤 原发性 转移性 病理诊断 

分 类 号：R735.36[医药卫生—肿瘤]