阿托伐他汀钙治疗急性脑梗死53例疗效研究  

Effect of atorvastatin calcium on 53 patients with acute cerebral infarction

作　　者：韩亚男[1] 

机构地区：[1]北京丰台医院神经内科,北京100071

出　　处：《中国现代医生》2017年第6期40-42,共3页China Modern Doctor

摘　　要：目的探讨阿托伐他汀钙治疗急性脑梗死的疗效。方法收集2013年1月~2016年1月我院收治的105例急性脑梗死患者,根据治疗方法不同,分为研究组和对照组,研究组53例,对照组52例,两组患者均给予常规治疗,在常规治疗的基础上,研究组给予阿托伐他汀钙治疗,比较两组临床疗效、NIHSS评分、BI评分。结果研究组的总有效率高于对照组,差异有统计学意义(P<0.05)。两组治疗后的NIHSS评分均较治疗前下降,BI评分均较治疗前提高,差异有统计学意义(P<0.05)。研究组治疗后的NIHSS评分较对照组低,BI评分较对照组高,差异均有统计学意义(P<0.05)。结论急性脑梗死患者使用阿托伐他汀钙治疗效果显著,能改善患者的神经功能缺损程度,促进日常生活能力的提高,建议临床推广应用。Objective To investigate the efficacy of atorvastatin calcium in the treatment of acute cerebral infarction. Methods A total of 105 patients with acute cerebral infarction admitted in our hospital from January 2013 to January 2016 were divided into study group（n=53） and control group（n=52） according to different treatment methods. The two groups were both given routine treatment.And the study group was given atorvastatin calcium treatment based on conventional treatment.Clinical efficacy, NIHSS score, BI score between the two groups were compared. Results The total effective rate of the study group was higher than that of the control group, and the difference was statistically significant （P〈0.05）. The NIHSS score of the two groups significantly decreased and the BI score was significantly higher, and which were statistically significant different compared with those before treatment（P〈0.05）. NIHSS score in the study group was obviously lower than that of the control group, and the BI score in the study group was significantly higher than that of the control group after treatment. The difference was statistically significant（P〈0.05）. Conclusion The treat- ment of atorvastatin calcium in patients with acute cerebral infarction is significant, which can improve the degree of neurological deficit and promote the improvement of daily living ability. And It is recommended to promote the clinical application of atorvastatin calcium.

关 键 词：脑梗死 阿托伐他汀钙 神经功能 日常生活能力 

分 类 号：R743.3[医药卫生—神经病学与精神病学]