Valpar职业评估训练系统对精神分裂症患者认知功能的影响  

Effect of Valpar occupational assessment training system on cognitive dysfunction in schizophrenia

作　　者：张国富[1] 任彩丽[1] 李达[1] 诸春明 Zhang Guofu Ren Caili Li Da Zhu Chunming(Wuxi Mental Health Center Affiliated Nanjing Medical University, Wuxi 214151, China)

机构地区：[1]南京医科大学附属无锡市精神卫生中心,无锡214151

出　　处：《中华行为医学与脑科学杂志》2017年第3期232-236,共5页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：无锡市医院管理中心医学科研项目（YGZX14080）

摘　　要：目的探讨Valpar职业评估训练系统对精神分裂症认知功能障碍的影响。方法收集门诊及住院精神分裂症患者60例，按照患者就诊顺序进行编号，按照随机数字表分为Valpar治疗组（研究组，n=30）及普通康复治疗组（对照组，n=30）。分别在在治疗前、治疗后6周，应用精神分裂症简明认知成套测评量表（BACS）及威斯康星卡片分类测验（WCST）进行评定，比较两组的评分变化情况。结果治疗后的6周评估结果显示，研究组BACS评分在符号编码（SC）[（37．50±6．50）分（t=-4．60，P〈0．01）]、代币运动（TM）[（60．80±8．72）分（t=-2．54，P=0．017）]、语言记忆（VM）[（44．40±11．29）分（t=-2．19，P=0．037）]、字词流畅性（WF）[（14．23±4．35）分（t=-3．39，P=0．002）]治疗前后差异有统计学意义。对照组仅在字词流畅性（WF）[（14．23±4．35）分（t=-3．39，P=0．002）]治疗前后差异有统计学意义。研究组WCST评分在错误应答数（Re）[（57．80±10．35）分（t=-3．06，P=0．005）]、持续性错误（Rpe）[（34．67±6．96）分（t=3．41，P=0．002）]，治疗前后差异有统计学意义，对照组在持续性错误（Rpe）[（34．30±7．01）分（t=4．36，P=0．000）]治疗前后差异有统计学意义。两组间比较，BACS评分在符号编码（SC）（t=2．010，P=0．048）、代币运动（TM）（t=2．124，P=0．038）差异有统计学意义；WCST评分在错误应答数（Re）（t=2．413，P=0．020）、持续性错误（Rpe）（t=2．009，P=0．047）差异有统计学意义。结论Valpar职业评估训练系统能显著改善精神分裂症的认知功能，提高治疗效果。Objective To explore the effect of Valpar occupational assessment training system on cognitive dysfunction in schizophrenia. Methods Sixty patients with schizophrenia were randomly assigned into Valpar therapy group （ experiment group, n = 30） and traditional rehabilitation therapy group （ control group, n= 30） according to the order number. The duration of the treatment was six weeks. The brief assessment of cognition in schizophrenia （BACS） and Wisconsin card sorting test （WCST） were conducted as pre- and post-treatment assessment. Results There were significant differences between scores of BASC in pre- and post-treatment assessment in experiment group. More specifically, the BASC scores in symbol coding （ 37.50±6.50, t= -4.60, P〈0.01 ） , token movement （ 60.80± 8.72, t= - 2.54, P= 0.017 ）, verbal memory （44.40±11.29, t=-2.19, P=0.037））,and word fluency（ 14.23±4.35, t=-3.39, P=0.002） were significantly different when comparing pre-and post-treatment assessment outcomes. In control group,the only significant difference was found in word fluency （ 14.23±4.35, t=-3.39, P= 0.002）.In addition,response errors （ 57.80±10.35, t=-3.06, P=0.005） and repeat errors （34.67±6.96, t=3.41, P=0.002） in WCST in experiment group were significantly different in pre-and post-treatment assessment while only repeat errors （ 34.30 ±7.01, t= 4.36, P= 0.000） was different in control group. It was further discovered that scores in in symbol coding（ t=2.010, P=0.048） ,token movement （ t=2.124, P=0.038） ,response errors （ t=2.413, P=0.020） and repeat errors （ t=2.009, P=0.047） in WCST were different between two groups. Conclusion Valpar professional evaluation training system can significantly improve the cognitive function of people with schizophrenia.

关 键 词：Valpar职业评估训练系统 精神分裂症 认知功能 

分 类 号：R749.3[医药卫生—神经病学与精神病学]