脑动脉瘤介入治疗后对比剂肾病的危险因素研究  

Risk factors of contrast-induced nephropathy after interventional treatment of cerebral aneurysms

作　　者：李珺[1] 梁月娥[2] 王湘[1] 钱东翔[1] 蔡名金[2] 

机构地区：[1]广州医科大学附属第三医院神经外科,广东广州510150 [2]广州医科大学附属第三医院放射科,广东广州510150

出　　处：《广州医科大学学报》2016年第5期34-36,共3页Academic Journal of Guangzhou Medical University

基　　金：广东省建设中医药强省科研课题项目(20141180)

摘　　要：目的:分析脑动脉瘤患者行介入治疗后对比剂肾病(CIN)的相关危险因素。方法:选取2013年6月到2015年12月在广州医科大学附属第三医院行介入治疗的110例脑动脉瘤患者为研究对象,根据术后血清肌酐浓度变化情况分为对比剂肾病组(CIN组)和非对比剂肾病组(非CIN组),分析CIN相关危险因素。结果:CIN组21例,非CIN组89例。糖尿病、慢性肾功能不全、高血压病与CIN相关,其中糖尿病、慢性肾功能不全为脑动脉瘤介入治疗后发生CIN的危险因素(P<0.05)。结论:糖尿病、慢性肾功能不全是脑动脉瘤介入治疗后对比剂肾病的重要危险因素,术前应做好预防措施。Objective：To analyze the risk factors of contrast-induced nephropathy （CIN） in patients with cerebral aneurysm underwent interventional therapy. Methods： A total of 110 patients with cerebral aneurysm, who underwent interventional therapy in the Third Affiliated Hospital of Guangzhou Medical University between June 2013 and December 2015, were included as the subjects in the study. According to the changes of postoperative serum creatinine concentration,all patients were divided into the contrast-induced nephropathy group （CIN group） and non-contrast-induced nephropathy （non-CIN group）. The CIN-related risk factors were analyzed. Results： There were 21 cases in CIN group and 89 cases in non-CIN group. Diabetes mellitus,chronic renal insufficiency and hypertension were correlated with CIN. Diabetes mellitus and chronic renal insufficiency were the risk factors of CIN after interventional treatment of cerebral aneurysms （P 〈 0.05 ）. Conclusion： Diabetes mellitus and chronic renal insufficiency are significant risk factors of CIN after interventional treatment of cerebral aneurysm,which should be prevented before the intervention.

关 键 词：脑动脉瘤 介入 对比剂肾病 

分 类 号：R732.21[医药卫生—肿瘤]