半夏等温化寒痰类中药的化学计量学研究  

Study on Pinelliae Ternata et al Traditional Chinese Medicines of Warming for Resolving Cold-Phlegm by Chemometrics

作　　者：申明金[1] 陈丽 曹洪斌[1] 

机构地区：[1]川北医学院化学教研室,南充637000 [2]南充武警医院内科,南充637000

出　　处：《世界中医药》2016年第10期2141-2144,共4页World Chinese Medicine

基　　金：川北医学院科研发展基金(编号:CBY13-A-ZP11)--中药半夏的化学模式识别研究

摘　　要：目的:探讨半夏等温化寒痰类中药之间的相互关系,为该类中药的组方研究提供启发和思路。方法:以8种中药的量化数据为研究对象,应用化学计量学中的数量化理论分类、系统聚类分析和模糊聚类方法进行信息解析。结果:3种聚类方法揭示半夏、天南星、白芥子、旋覆花和白前之间具有较高的相似性,其他药物之间的药性差异较大。结论:应用化学计量学方法研究半夏等温化寒痰类中药之间的相互关系,为中药研究提供了新的思路。Objective： To discuss the relationship in Chinese medicinal of warming for resolving cold-phlegm,such as Pinelliae ternate,so as to provide a new way for the further studies on the prescription composition rules. Methods： The quantified results of8 kinds Chinese medicinal were selected as subject of research and information analysis was carried out by quantification theory,cluster analysis and fuzzy clustering of chemometrics. Results： The results of three kinds of clustering classification revealed that there was high similarity among Pinelliae ternata,Arisaema erubescens,Sinapi alba L,Inula japonica Thunb and Cynanchum stauntonii. However,there was great difference among the other three kinds Chinese herbs. Conclusion： The method of chemometrics applied in study on the relationship in Chinese medicines of warming for resolving cold-phlegm may provide a new way for Traditional Chinese medicines.

关 键 词：半夏 中药 化学计量学 数量化理论 聚类分析 模糊聚类 

分 类 号：R311[医药卫生—基础医学]