认知行为疗法治疗产后抑郁的系统评价和Meta分析  

Influence of Cognitive Behavioral Therapy for Treating Postnatal Depression: A Systematic Review and Meta Analysis

作　　者：佘芹[1] 成志[1] 彭翠[1] 谭卫荷[1] 郭晓燕[1] 

机构地区：[1]广东省清远市人民医院,广东清远511518

出　　处：《中国医学创新》2017年第10期92-96,共5页Medical Innovation of China

摘　　要：目的:系统评价认知行为疗法治疗产后抑郁(PPD)的效果,为临床治疗提供依据。方法:通过计算机检索数据库,纳入随机对照试验(RCT)文献;评价其研究质量、提取资料;采用Rev Man 5.3软件进行Meta分析。结果:共纳入13个RCT研究、2050例患者。有10项研究评价为B级,3项评价为C级。根据疗效评估量表的不同,评估结果数据是否有具体的均数和标准差及文献质量评价,共筛选出6项研究纳入Meta分析,并进一步分为爱丁堡产后抑郁量表(EPDS)和贝克抑郁量表(BDI)两个亚组,Meta分析结果均显示:认知行为疗法组与常规护理组抑郁症状改善的差异有统计学意义即EPDS亚组:WMD=3.98,95%CI(2.65,5.30),P<0.000 01;BDI亚组:WMD=5.7,95%CI(3.11,8.29),P<0.000 01。结论:认知行为疗法可以改善产后抑郁患者的抑郁情绪。Objective： To evaluate the effect of cognitive behavioral therapy on improving depression on patients with postnatal depression.Method： Related databases were searched to find related randomized control trails （ RCT ） .The quality of these RCT was evaluated.Meta analysis was conducted using Rev Man 5.3.Result： 13 RCTs involving 2050 patients were identified.As to the quality level, 10 literatures were grade B, and 3 literatures were grade C.6 RCTs were divided into two sub-group.Meta-analysis indicated that cognitive behavioral therapy significantly improved depression, EPDS： WMD=3.98, 95%CI （2.65, 5.30）, P〈0.000 011; BDI： WMD=5.7, 95%C1 （ 3.11, 8.29 ）, P〈0.000 01.Conclusion： Cognitive behavioral therapy can reduce depression of patients with postnatal depression.

关 键 词：认知行为疗法 产后抑郁 系统综述 META分析 

分 类 号：R749.4[医药卫生—神经病学与精神病学]