1545例肝硬化患者病因分析  

Analysis of etiology of 1545 patients with liver cirrhosis

作　　者：吴安燕 邓世康[2] 杨晋辉[1] 

机构地区：[1]昆明医科大学第二附属医院肝病中心,云南昆明650101 [2]昆明理工大学附属医院肝胆外科,云南昆明650032

出　　处：《云南医药》2017年第2期109-111,共3页Medicine and Pharmacy of Yunnan

基　　金：昆明理工大学引进人才科研启动基金项目(KKSY201660007)

摘　　要：目的探讨肝硬化的病因特点。方法按照病毒性肝硬化、自身免疫性肝硬化、血吸虫性肝硬化、酒精性肝硬化、药物性及原因不明肝硬化对住院肝硬化患者进行病因分析,采用描述性统计分析。结果 1 545例肝硬化患者中,引起肝硬化的病因主要为病毒性肝炎,以乙肝病毒和丙肝病毒感染最常见,单纯乙肝病毒感染占56.38%,单纯丙肝病毒感染占15.08%,乙肝病毒与丙肝病毒合并感染占0.39%。自身免疫性肝病导致的肝硬化的比例在上升,原发性胆汁性肝硬化占19.09%,自身免疫性肝硬化占3.50%。血吸虫性肝硬化导致的肝硬化的比例在下降,占0.84%。结论在感染性肝病诊断和治疗逐渐规范化的同时,应注重非病毒性肝病的诊治,以减少越来越常见的非病毒性肝病导致的肝硬化。Objective To investigate the etiology of patients with liver cirrhosis in hospital. Methods The etiology of patients with liver cirrhosis was conducted according to infectious disease of the liver, autoimmune liver disease, schistosoma cirrhosis, alcoholic liver disease, drug and liver disease of unknown cause, using descriptive statistical analysis. Results All of 1 545 patients with liver cirrhosis in hospital were analyzed.Etiology analysis showed that infectious disease of the liver （including HBV, HCV） were the most common, 56.38% patients were with the simple HBV infection, 15.08% patients were with the simple HCV infection and 0.39% patients were with the HBV and HCV infection. The composition ratio of the autoimmune liver disease appeared of increasing trends, the 19.09% patients were with the primary biliary cirrhosis, and the 3.50% patients were with the autoimmune liver disease. The composition ratio of the schistosoma cirrhosis appeared of declining trends, the 0.84% patients were with the schistosoma cirrhosis. Conclusions The quantity of patients with liver cirrhosis will be reduced through paying more attention to non-viral liver diseases.

关 键 词：肝硬化 病因 回顾性分析 

分 类 号：R575.2[医药卫生—消化系统]