急性脑梗死患者中H型高血压与颈动脉粥样硬化斑块关系的研究  

Research of Carorid Atherosclerotic Plaque and H-Type Hypertension in Patients with Acute Cerebral Infarction

作　　者：姜昆 崔荣[2] 胡艳丽 白萍 

机构地区：[1]黑龙江省社会康复医院,黑龙江哈尔滨150030 [2]哈尔滨市南岗区大成社区卫生服务中心,黑龙江哈尔滨150007 [3]黑龙江省海员总医院,黑龙江哈尔滨150020

出　　处：《黑龙江医学》2017年第3期197-198,共2页Heilongjiang Medical Journal

摘　　要：目的探讨急性脑梗死患者中颈动脉粥样硬化斑块对H型高血压的影响。方法采用横断面研究,连续收集哈尔滨医科大学附属第一医院神经内科2011-01—2014-05间新发急性脑梗死住院患者3963例,调查及记录入院时的血浆同型半胱氨酸、血脂及有无颈动脉粥样硬化斑块。结果 H型高血压组2147例,非H型高血压组1816例。糖尿病、冠心病、吸烟史两组间的差异均有统计学意义(P<0.05),而年龄、性别、饮酒史方面差异无统计学意义(P>0.05)。非H型高血压组的高密度脂蛋白高于H型高血压组,差异有统计学意义(P<0.05);总胆固醇、甘油三酯、低密度脂蛋白水平两组间差异无统计学意义(P>0.05)。非H型高血压组与H型高血压组单因素分析结果显示,OR=1.487,95%CI(1.239~1.784),有统计学意义;调整年龄、性别、糖尿病史、冠心病史、吸烟史、饮酒史、血脂后OR=1.476,95%CI(1.217~1.790),有统计学意义。结论 H型高血压增加颈动脉粥样硬化斑块的危险性。Objective To investigate the effect of carotid atherosclerotic plaque and H-type hypertension in patients with acute cerebral infarction.Methods Using cross sectional study to research 3963 cases of hospitalized patients with primary acute cerebral infarction from January,2011 to May,2014 in The First Affiliated Hospital of Harbin Medical University,to investigate and record the plasma homocysteine and blood lipid with or without carotid atherosclerotic plaque in patients.Results There are H-type hypertension group （2147 cases） and non-H-type hypertension group（1816 cases）.There are statistically significant differences of diabetes,coronary heart disease and smoking history between the two groups （P〈0.05）.But there is no significant difference of age,sex,and drinking history（P〉0.05）.The high density lipoprotein in the non-H-type hypertension group is higher than that of the H-type hypertension group,and it has statistical significance（P〈0.05）;there is no significant difference in the levels of total cholesterol,triglyceride,low density lipoprotein between two groups （P〉0.05）.Single factor analysis of non-H-type hypertension group and H-type hypertension group shows that OR=1.487,95%CI：1.239~1.784,the difference is statistically significant.Through adjusting age,sex,history of diabetes,history of coronary heart disease,smoking history,drinking history,blood lipid,OR=1.476,95%CI：1.217~1.790,they still have statistical significance.Conclusion H-type hypertension increases the risk of carotid atherosclerotic plaque.

关 键 词：急性脑梗死 H型高血压 颈动脉粥样硬化斑块 

分 类 号：R743.3[医药卫生—神经病学与精神病学]