喹啉-8-甲醛缩4-甲基氨基硫脲Ni(Ⅱ)/Zn(Ⅱ)/Cd(Ⅱ)/Cu(Ⅱ)配合物的合成、结构和DNA结合性质（英文）  

Syntheses,Crystal Structures and DNA-Binding Properties of Ni(Ⅱ)/Zn(Ⅱ)/Cd(Ⅱ)/Cu(Ⅱ)Complexes with 4-Methyl-1-((quinolin-8-yl)methylene)-thiosemicarbazide

作　　者：毛盼东 韩学锋[2] 李珊珊[1] 史琳莹 王元[1] 吴伟娜[1] 

机构地区：[1]河南理工大学化学化工学院,焦作454000 [2]河南理工大学人事处,焦作454000

出　　处：《无机化学学报》2017年第4期692-698,共7页Chinese Journal of Inorganic Chemistry

基　　金：国家自然科学基金(No.21001040);河南省教育厅自然科学基金(No.12B150011,14B150029)资助项目

摘　　要：合成并通过单晶衍射、元素分析、红外光谱表征了配合物[NiL_2]·2CH_3OH(1),[ZnL_2]·CH_3OH(2),[CdL_2]·CH_3CH_2OH(3)和[Cu_2L_2Cl_2](4)(HL为喹啉-8-甲醛缩4-甲基氨基硫脲)。单晶衍射结果表明,配合物1~3结构相似,中心金属离子与来自2个硫醇化脱质子配体L-的4个N原子和2个S原子配位,采取扭曲的八面体配位构型。而配合物4中Cu(Ⅱ)离子与1个中性配体HL和3个氯离子配位,其中2个氯离子为μ~2桥联。荧光光谱结果表明,所有配合物,尤其是4与DNA的相互作用能力明显强于配体。Four complexes[NiL2]·2CH3OH （1）,[ZnL2]·CH3OH （2）,[CdL2]·CH3CH2OH （3） and[Cu2L2Cl2] （4） （HL=4-methyl-1-（（quinolin-8-yl）methylene）-thiosemicarbazide） have been synthesized and structurally determined by single-crystal X-ray diffraction. The results show that the structures of complexes 1-3 are quite similar. The metal ion in each complex with a distorted octahedron geometry is surrounded by two anionic thiosemicarbazone ligands with N4S2 donor set. However, complex 4 is binuclear, and each central Cu（Ⅱ） ion is coordinated by one independent neutral ligand HL and three chloride anions, two of which act as μ2-bridges. In addition, the fluorescence spectra indicate that the interactions of the complex es with DNA, particularly of the complex 4, are stronger than that of the ligand HL.

关 键 词：喹啉 缩氨基硫脲 配合物 晶体结构 DNA相互作用 

分 类 号：O614.813[理学—无机化学] O614.241[理学—化学]