The role of wildlife (wild birds)in the global transmission of antimicrobial resistance genes  

作　　者：Jing Wang Zhen-Bao Ma Zhen-Ling Zeng Xue-Wen Yang Ying Huang Jian-Hua Liu 

机构地区：[1]College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China

出　　处：《Zoological Research》2017年第2期55-80,共26页动物学研究（英文）

基　　金：partially supported by grants from the National Key Basic Research Program of China(2013CB127200);the National Natural Science Foundation of China(81661138002)

摘　　要：Antimicrobial resistance is an urgent global health challenge in human and veterinary medicine. Wild animals are not directly exposed to clinically relevant antibiotics; however, antibacterial resistance in wild animals has been increasingly reported worldwide in parallel to the situation in human and veterinary medicine. This underlies the complexity of bacterial resistance in wild animals and the possible interspecies transmission between humans, domestic animals, the environment, and wildlife. This review summarizes the current data on expanded- spectrum 13-1actamase （ESBL）, AmpC IB-lactamase, carbapenemase, and colistin resistance genes in Enterobacteriaceae isolates of wildlife origin. The aim of this review is to better understand the important role of wild animals as reservoirs and vectors in the global dissemination of crucial clinical antibacterial resistance. In this regard, continued surveillance is urgently needed worldwide.Antimicrobial resistance is an urgent global health challenge in human and veterinary medicine. Wild animals are not directly exposed to clinically relevant antibiotics; however, antibacterial resistance in wild animals has been increasingly reported worldwide in parallel to the situation in human and veterinary medicine. This underlies the complexity of bacterial resistance in wild animals and the possible interspecies transmission between humans, domestic animals, the environment, and wildlife. This review summarizes the current data on expanded- spectrum 13-1actamase （ESBL）, AmpC IB-lactamase, carbapenemase, and colistin resistance genes in Enterobacteriaceae isolates of wildlife origin. The aim of this review is to better understand the important role of wild animals as reservoirs and vectors in the global dissemination of crucial clinical antibacterial resistance. In this regard, continued surveillance is urgently needed worldwide.

关 键 词：AMPC ESBLS IMP  mcr-1 NDM Wild birds 

分 类 号：S859.79[农业科学—临床兽医学]