老年抑郁症患者认知功能受损与共病数量、抑郁程度相关性分析  

The Correlation Research of Cognitive Function Damage,Co-morbidity Numbers and Depression Degree in Elderly Depression

作　　者：秦碧勇[1] 戴立磊 郑艳[3] 

机构地区：[1]湖北医药学院附属人民医院神经内科,湖北十堰442000 [2]武汉市精神卫生中心,湖北武汉430000 [3]湖北医药学院附属人民医院护理部,湖北十堰442000

出　　处：《湖北医药学院学报》2017年第1期20-23,共4页Journal of Hubei University of Medicine

基　　金：湖北省教育厅人文社会科学基金项目(16Q193);湖北省教育厅科学技术基金项目(B2016500)

摘　　要：目的:探讨老年抑郁症患者共病的现状,并分析认知功能受损与共病数量及抑郁程度的相关性。方法:使用一般情况调查表、老年抑郁量表(GSD)和简易智力状态检查表(MMSE)对我院住院及门诊184例老年抑郁症患者进行调查,按认知功能是否受损分为受损组121例,非受损组63例。结果:⑴两组患者一般资料比较,在年龄、受教育程度、有无子女、有无配偶上差异均有统计学意义(P<0.05);⑵老年抑郁症患者共病的现状:呼吸系统疾病73.4%,高血压68.5%,糖尿病66.8%,消化系统疾病39.7%,冠心病28.8%,外伤7.1%,肿瘤3.3%,脑中风2.7%;⑶受损组患者的共病数量及GSD评分明显高于未受损组患者,差异有统计学意义(P<0.01);⑷MMSE评分与共病数量、GDS评分、年龄、有无子女均呈负相关,与受教育程度呈正相关;多元线性逐步回归分析,得出方程为Y=0.353×1(受教育程度)-0.965×2(共病数量)+28.323。结论:老年抑郁症认知功能受损的患者年龄明显较大、受教育程度较低、无配偶及子女;共病疾病中更多见的是呼吸系统疾病、高血压、糖尿病等;年龄、子女、共病数量、受教育程度、抑郁程度等与患者认知功能受损相关。受教育程度和共病数量是认知功能受损的影响因素。Objective To investigate the status of elder depression co-morbidity and analyzes the correlation in cognitive function damage,co-morbidity numbers and depression degree. Methods 184 elderly depression in inpatient department and ambulant clinic of Hospital are all measured with general questionnaire,GSD and MMSE. We divided all the subjects into two groups according to whether the cognitive function was damaged,which are cognitive function damage 121 cases and cognitive function normal 63 cases. Results There＇re statistically significant differences between the two groups of average data in age,education level,having children and having spouse（P 0.05）; The status of elderly depression co-morbidity： respiratory diseases（73.4%）,hypertension（68.5%）,diabetes（66.8%）,digestive disease（39.7%）,coronary heart disease（28.8%）,traumatism（7.1%）,tumour（3.3%）,stroke（2.7%）; The number of co-morbidity and scores of GSD in cognitive function damage is significantly higher than that in normal（P〈0.01）; The scores of MMSE are positively correlated with the education level（P〈0.05） and negative correlated with co-morbidity number,the scores of GSD,the age and having children or not（P〈0.05）. The multiple linear regression is Y = 0.353× 1（education level）-0.965× 2（comorbidity number） ＋ 28. 323. Conclusion The elderly depressions with cognitive function damage are correlated with old age,lower education level and no children. The most common of co-morbidity in the elderly depression are respiratory diseases,hypertension and diabetes. Age,children,co-morbidity number,degree of education and depression are correlated with the cognitive function damage. Education level and co-morbidity number are speculated to be significance to cognitive function damage.

关 键 词：老年抑郁症 共病 认知功能 抑郁程度 横断面调查 

分 类 号：R749.4[医药卫生—神经病学与精神病学]