Potassium tert-Butanolate Promoted Reaction ofBenzaldehydes and Indoles: a New Strategy for Synthesis of Bis(indolyl)arylmethanes  

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作  者:JIANG Chong LI Jue LU Guanghui ZHENG Yang YU Xinling LU Songyang HAI Li WU Yong 

机构地区:[1]Key Laboratory of Drug-tavgeting, Education Ministry, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China [2]Department of Pharmacy, Taihe Hospital Hubei University of Medicine, Shiyan 442000, P R. China

出  处:《Chemical Research in Chinese Universities》2017年第2期200-205,共6页高等学校化学研究(英文版)

摘  要:t-BuOK-promoted synthesis of bis(indolyl)arylmethunes from aromatic aldehydes and indoles wasachieved. Substrates bearing different functional groups, especially groups which are sensitive to acidic media, arewell tolerated under the optimal condition, making this reaction particularly attractive for expanding the scope of thepresent protocols that provides bis(1H-indol-3-yl)arylmethanes.

关 键 词:Bis(indolyl)arylmethane INDOLE Base-promoted REACTION 

分 类 号:O[理学]

 

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