泮托拉唑与兰索拉唑治疗幽门螺旋杆菌感染活动性胃溃疡成本—效果对比分析  

Cost-effect comparison analysis of pantoprazole and lansoprazole on Helicobacter pylori infection in active gastric ulcer

作　　者：潘虹[1] PAN Hong(Department of Pharmacy, The First People＇s Hospital of Liangshan Prefecture, Sichuan Province, Liangshan Prefecture 615000, China)

机构地区：[1]凉山州第一人民医院药剂科,四川省西昌市615000

出　　处：《临床合理用药杂志》2017年第10期18-19,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的对比泮托拉唑与兰索拉唑治疗幽门螺旋杆菌感染活动性胃溃疡的成本—效果。方法将180例幽门螺旋杆菌感染活动性胃溃疡患者依据随机数字表法分为A组和B组各90例,A组给予泮托拉唑联合克拉霉素片、阿莫西林胶囊治疗,B组给予兰索拉唑联合克拉霉素片、阿莫西林胶囊治疗,对比分析2组临床疗效和成本—效果差异。结果 2组临床疗效比较差异无统计学意义(P>0.05)。A组患者治疗经济学成本—效果优于B组,差异有统计学意义(P<0.05)。结论幽门螺旋杆菌感染活动性胃溃疡患者采取泮托拉唑进行治疗不仅临床效果显著,而且其成本—效果明显优于兰索拉唑治疗方案,值得推广。Objective To compare the cost-effect of pantoprazole and lansoprazole in the treatment of Helicobacter pylori infection with active gastric ulcer. Methods 180 patients of Helicobacter pylori infection with active gastric ulcer,according to random number table method,were randomly divided into group A and group B,each of 90 cases. Group A was treated with pantoprazole,clarithromycin and amoxicillin; group B was treated with lansoprazole,clarithromycin and amoxicillin. The clinical efficacy and cost-effect differences were compared between two groups. Results There was no significant difference in clinical efficacy between two groups（ P〉0. 05）. The cost-effect of treatment in group A was better than that in group B,the difference was statistically significant（ P〈0. 05）. Conclusion The treatment of pantoprazole in Helicobacter pylori infection patients with active gastric ulcer is not only significant clinical effect,and its cost-effect was significantly better than lansoprazole treatment program,it is worth promoting.

关 键 词：成本—效果 活动性胃溃疡 泮托拉唑 幽门螺旋杆菌 兰索拉唑 

分 类 号：R573.1[医药卫生—消化系统]