庆大霉素局部冲洗预防种植术后早期创口感染的研究  

Prevention of early wound infection with topical gentamincin rinsing in implant surgery

作　　者：王璐璐[1] 许立[1] 杜进辉 张兰 陈建钢[1] 

机构地区：[1]武汉大学中南医院口腔科,湖北武汉430071 [2]湖北省中西医结合医院口腔科,湖北武汉430015

出　　处：《临床口腔医学杂志》2017年第3期162-164,共3页Journal of Clinical Stomatology

摘　　要：目的:探讨庆大霉素局部冲洗对非翻瓣种植术后早期创口感染的预防作用。方法:将29例非翻瓣种植修复患者随机分为庆大霉素组(实验组)16例和生理盐水组(对照组)13例。观察比较种植术后1 d、3 d、7 d,两组患者术后局部疼痛指数(PI)、龈沟出血指数(SBI)、种植体周软组织指数(PIST)、龈沟液量(PICF)及龈沟液内白介素6(IL-6)含量的变化。结果:术后1周内实验组与对照组比较,前者PI、SBI、PIST、PICF及IL-6含量均有明显改善(P<0.05)。结论:术中庆大霉素局部冲洗可明显减轻炎症反应,有效预防种植术后软组织感染。Objective：To investigate the prophylactic effect of local flushing gentamincin on wound healing following flapless implant surgery .Methods：Twenty-nine flapless implant cases were randomized into gentamicin group with 16 cases and normal saline group（control group）with 13 cases.The pain index（PI）,gingival sulcus bleeding index （SBI）,peri-im-plant soft tissue index （ PIST ） , peri-implants crevicular fluid （ PICF ） volume and crevicular interleukin 6 （ IL-6 ） level of 2 groups were compared respectively after 1 day,3 days,7 days of operation .Results：Within 1 week,gentamicin group showed lower index values comparing with the control group in PI ,SBI,PIST,PICF volume and IL-6 level（P〈0.05）.Conclusion：Topical gentamincin rinsing could reduce inflammation response in wound healing .Therefore,it is recommended to use gen-tamincin to prevent early wound infection in implant surgery .

关 键 词：种植体周龈沟液 庆大霉素 白介素6 创口早期感染 

分 类 号：R782.1[医药卫生—口腔医学]