健脾活血中药联合化疗治疗大肠癌术后患者临床观察  

Clinical Observation of Strengthening Spleen and Activating Blood Herbs Combined with Chemotherapy in Treating Postoperative Large Intestine Cancer Patients

作　　者：展鹏远[1] 

机构地区：[1]河南大学第一附属医院普外科,河南开封475000

出　　处：《新中医》2017年第4期116-118,共3页New Chinese Medicine

摘　　要：目的:观察健脾活血中药联合化疗在大肠癌术后治疗中的临床疗效。方法:选择76例大肠癌术后患者为研究对象,以随机数字表法分为2组各38例,对照组单纯采用化疗治疗,观察组采用健脾活血中药联合化疗治疗,对2组患者生存状态、生活质量、不良反应发生情况等进行观察。结果:观察组患者6月死亡率15.79%,中位生存时间(26.12±5.18)月,对照组患者6月死亡率39.47%,中位生存时间(20.67±8.44)月,2组死亡率、中位生存时间分别比较,差异均有统计学意义(P<0.01);治疗后,观察组Karnofsky评分较对照组高,美国中部肿瘤协作组(ECOG)评分较对照组低,差异均有统计学意义(P<0.01);观察组治疗后不良反应程度低于对照组,差异有统计学意义(P<0.05)。结论:健脾活血中药配合化疗可延长大肠癌患者术后生存时间,也能减轻化疗不良反应,对提高患者生活质量具有重要作用。Objective：To observe the clinical effect of strengthening spleen and activating blood herbs combined with chemotherapy in treating postoperative large intestine cancer patients.Methods：Selected 76 postoperative large intestine cancer patients as research objects,and divided them into two groups with 38 cases in each,according to the random table method.The control group was given simple treatment of chemotherapy,and the observation group was given strengthening spleen and activating blood herbs combined with chemotherapy.Observed survival time,quality of life,adverse reaction of the two groups.Results：Six months mortality and median survival time of the observation group was 15.79%and（26.12±5.18）months respectively;In the control group,six months mortality and median survival time was 39.47%and（20.67± 8.44）months respectively,the difference being significant（P〈0.01）.After treatment,Karnofsky score of the observation group was higher than that of the control group,and the Eastern Cooperative Oncology Group（ECOG） score and adverse reaction degree of the observation group was lower than that of the control group,the differences being significant（P〈0.01,P〈0.05）.Conclusion：Strengthening spleen and activating blood herbs combined with chemotherapy can prolong the survival time of postoperative large intestine cancer patients,and also can reduce the adverse reactions of chemotherapy,which is very important in improving the quality of life of patients.

关 键 词：大肠癌术后 中医疗法 健脾活血 化学疗法 6月死亡率 中位生存时间 KARNOFSKY评分 美国中部肿瘤协作组(ECOG) 

分 类 号：R735.34[医药卫生—肿瘤]