喉非霍奇金淋巴瘤的临床分析  

Clinical analysis of laryngeal non-Hodgkin's lymphoma

作　　者：陈乐[1] 张明[1] 李采[1] 周梁[1] 朱嘉兴[2] 王纾宜[2] 

机构地区：[1]上海复旦大学附属眼耳鼻喉科医院耳鼻咽喉科,上海200031 [2]上海复旦大学附属眼耳鼻喉科医院病理科

出　　处：《临床耳鼻咽喉头颈外科杂志》2017年第7期546-548,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：上海市自然科学基金项目(No:13ZR1406200;17ZR1404700);上海市浦东新区卫生局卫生(计生)科技项目(No:PW2016D-11)

摘　　要：目的:探讨喉非霍奇金淋巴瘤(NHL)的临床表现、病理特征及治疗。方法:回顾性分析我院诊治的31例喉NHL患者的临床资料。结果:31例患者中T细胞淋巴瘤5例(16.1%),B细胞淋巴瘤10例(32.3%),NK/T细胞淋巴瘤11例(35.5%),混合型和未定型淋巴瘤5例(16.1%)。病变位于声门上区27例(87.1%),声门区1例(3.2%),声门及声门下3例(9.7%)。结论:喉NHL临床罕见,好发于声门上区,确诊有赖于免疫组织化学检查,化疗和放疗是主要的治疗手段。Objective： To analyze the clinical characteristics, pathology and treatment of laryngeal non- Hodgkin＇s lymphoma. Method.. Clinical information of 31 patients with laryngeal non-Hodgkin＇s lymphoma treated in our hospital was reviewed retrospectively. Result： T cell lymphoma, B cell lymphoma, NK/T cell lymphoma, the mixed pattern and unspecified lymphoma accounted for 16.1% （5/31）, 32.3% （10/31）, 35.5% （11/31） and 16.1% （5/31） of the patients, respectively. Twenty-seven cases were located in supraglottic region, 1 case was located in glottic region, and 3 eases were located in glottic and subglottic region. Conclusion.. The laryngeal non- Hodgkin＇s lymphoma was a rare malignant neoplasm and the most localized in the supraglottic region. Its diagnosis depended on comprehensive immunohistochemistry examination. Chemotherapy and radiotherapy were the main therapeutic methods.

关 键 词：喉肿瘤 非霍奇金淋巴瘤 免疫组织化学 

分 类 号：R739.65[医药卫生—肿瘤]