广州市海珠区2008～2015年结直肠癌发病现状及趋势分析  

Analysis of Colorectal Cancer Incidence Trend in Guangzhou Haizhu District from 2008 to 2015

作　　者：郭钜旋[1] 张晓[1] 庄晓霞[1] 于海波[1] 吴辉绪[1] 林国桢[2] Guo Juxuan Zhang xiao Zhuang Xiaoxia Yu Haibo Wu Huixu Guozhen(Haizhu District of Guangzhou Center for Disease Control and Prevention, Guangzhou 510288, China Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China)

机构地区：[1]广州市海珠区疾病预防控制中心,广州510288 [2]广州市疾病预防控制中心,广州510080

出　　处：《肿瘤预防与治疗》2017年第2期116-120,共5页Journal of Cancer Control And Treatment

基　　金：广东省自然科学基金项目(编号:2016A030313504)

摘　　要：目的:了解2008~2015年广州市海珠区结直肠癌发病情况,分析发病趋势,为我区结直肠癌防控工作提供科学依据。方法:根据广州市肿瘤登记处2008~2015年的恶性肿瘤发病数据,计算发病例数、粗发病率、年龄别发病率、中国标化发病率(中标率)、世界标化发病率(世标率)、年均增长率,利用Join Point软件对发病率变化趋势进行分析,计算年度变化百分比(APC值)。结果:2008~2015年广州市海珠区结直肠癌发病率61.48/10万,其中男性66.18/10万,女性56.66/10万;中标率25.73/10万,其中男性29.03/10万,女性22.63/10万;世标率34.83/10万,其中男性39.48/10万,女性30.54/10万。2008~2015年,海珠区结直肠癌发病率以6.49%的速度上升,男性上升速度为8.23%,女性上升速度为4.55%,男性快于女性。调整年龄结构后,上升速度变缓,以每年0.28%的速度上升,男性上升速度为1.84%,而女性为下降趋势,APC值为-1.73%。结论:2008~2015年广州市海珠区结直肠癌发病率高于全国平均水平,总体呈上升趋势。应加强结直肠癌的综合防控工作,提高早诊早治水平。Objective： To investigate the trends in colorectal cancer incidence in Guangzhou Haizhu District from 2008 to 2015. Methods： The data from Guangzhou Cancer Registry were collected to calculated the number of cases, crude incidence rate, incidence by age, while the age -standardized rate （ASR） was standardized by China＇ s and world＇ s population age structure. The incidence trend was analyzed, and the annual percentage change （APC） was calculated by the JoinPoint software. Results： From 2008 to 2015, the colorectal cancer incidence of Haizhu District was 61.48/10s ,66. 18/10s in male, 56.66/10s in female; ASR of China was 25.73/10s ,29.03/105 in male,22.63/105 in female; ASR of the world was 34.83/105 ,39.48/105 in male,30.54/105 in female. The colorectal cancer crude incidence has increased both in male and female from 2008 to 2015, the APC value was 6.49% ,8.23% in male and 4.55% in female. After adjusted by age structure, the uptrend became gently, with the APC value increased by 0.28% , male increased 1.84% , while the fe- male decreased by 1.73%. Conclusion： The colorectal cancer incidence in Guangzhou Haizhu District was higher than the national average and appeared overall uptrend. The comprehensive prevention and control of colorectal cancer should be strengthened to improve the level of early diagnosis and treatment.

关 键 词：结直肠癌 发病率 流行病学 广州市 

分 类 号：R735.34[医药卫生—肿瘤]