Klinefelter综合征合并2型糖尿病一例  

A case report of Klinefelter's syndrome with type 2 diabetes mellitus

作　　者：杜婧[1] 邬月琴[1] 魏枫[1] 卫晶晶[1] DU Jing WU Yue-qin WEI Feng et al.(Department of Endocrinology, The First Affiliated Hospital, BaoTou Medical College, Baotou 014010 ,China)

机构地区：[1]包头医学院第一附属医院内分泌科,014010

出　　处：《中国糖尿病杂志》2017年第4期363-364,共2页Chinese Journal of Diabetes

摘　　要：患者男,28岁,主因"体重下降3年,发现血糖高伴性功能障碍1年"于2016年3月29日就诊入院。1年前因"龟头炎"就诊时发现血糖高,诊断为糖尿病,目前口服二甲双胍控制血糖。入院查体:身材瘦长,体重86.5 kg,身高185 cm,指尖距182.8 cm,皮肤白净细腻,无胡须,喉结不明显,阴毛腋毛稀疏,乳房发育,阴茎短小;两次精液常规检查均无法获得标本;彩超提示双侧睾丸体积偏小;化验检查促性腺激素高于正常而睾酮低于正常;染色体核型47XXY,诊断Klinefelter综合征(KS)合并T2DM。A 28-year-old male patient was admitted to our hospital on March 29,2016,because of weight loss for three years, hyperglycemia and libido loss for one year. He was diagnosed as type 2 diabetes one year ago and treated with Metformin. Physical examination showed slender body with weight 86.5 kg,height 185 cm, arm span 182.8 cm, skin white and exquisite, no beard, sparse armpit and body hair, short penis and gynecomastia. Two semen examinations could not get specimen. Ultrasound showed that the testicular volume was small. The level of gonadotropin was higher and testosterone was lower than normal control. Chromosome karyotype was 47XXY. He was diagnosed as Klinefelter＇ s syndrome complicated with type 2 diabetes mellitus.

关 键 词：KLINEFELTER综合征 糖尿病 2型 

分 类 号：R587.1[医药卫生—内分泌] R596.1[医药卫生—内科学]