福建省局部地区消化系统主要癌种空间自相关分析  

Spatial auto-correlation of main digestive system cancers in parts of Fujian province

作　　者：林永添[1,2] 陶韬[2] 袁平[3] 吴思英[2] 

机构地区：[1]福建省肿瘤医院流行病室,福州350014 [2]福建医科大学公共卫生学院流行病与卫生统计系福建省环境因素与肿瘤重点实验室 [3]福建省疾病预防控制中心

出　　处：《中国公共卫生》2017年第4期622-625,共4页Chinese Journal of Public Health

基　　金：国家临床重点专科建设项目;福州市科技计划项目(2015-S-163)

摘　　要：目的探索福建省部分肿瘤登记地区以乡镇为尺度的食管癌、胃癌、结直肠癌和肝癌等消化系统主要恶性肿瘤空间分布特征和聚集性。方法于2007—2012年以福建省长乐市、涵江区和福清市3个肿瘤登记处作为研究现场,收集4种消化系统主要恶性肿瘤分乡镇发病率,应用Arc GIS 10.3软件进行全局和局部Moran's I、G统计量自相关分析。结果食管癌、胃癌、结直肠癌和肝癌全局Moran's I分别为0.734 011、0.932 897、0.633 696和0.644 418(均P<0.001);食管癌、胃癌、结直肠癌全局G统计量分别为0.000 024、0.000 020和0.000 017(均P<0.001)。局部Moran's I自相关显示,食管癌有11个H-H(高-高值)区域;胃癌有8个H-H区域、7个L-L(低-低值)区域;结直肠癌有8个H-H区域、1个H-L(高-低值)区域、6个L-L区域;肝癌有11个H-H区域、1个L-H(低-高值)区域、8个L-L区域。局部G自相关结果显示,食管癌有3个冷点和1个热点;胃癌有4个冷点和2个热点;结直肠癌有6个冷点和1个热点;肝癌有1个冷点和2个热点。结论消化系统主要恶性肿瘤在乡镇级别空间上呈现非随机分布,4个癌种均有其独特的热点、冷点以及发病率高低交错的聚集区域。Objective To explore the distribution and spatial clustering of esophageal, gastric, colorectal, and liver cancer at township level in some regions covered by cancer registration system in Fnjian province with spatial auto-corre- lation analysis and to provide evidences for early screening and effective prevention and control of the cancers. Methods Data on incidence of esophageal, gastric, colorectal, and liver cancer and demographic information were collected from the residents in Changle city, Fuqing city and Hanjiang District of Fujian province during the period from 2007 to 2012. Software ArcGIS 10. 3 was used to analyze the incidence of the cancers with the global and local Moran＇s I and G statis- tics of spatial auto-correlation analysis. Results The global Moran＇s I index for esophageal, gastric, coloreetal, and liver cancer incidence in the areas studied were 0. 734 011,0. 932897,0. 633 696,and 0. 644 418,respectively （P 〈0. 001 for all ） ;the global G index for esophageal, gastric, and colorectal cancer were 0. 000 024,0. 000 020, and 0. 000 017, respec-tively （P 〈 0. 001 for all）. The local Moran＇s I indexes revealed 11 high-high regions for esophageal cancer,8 high-high regions and 7 low-low regions for gastric cancer,8 high-high regions and one high-low region and 6 low-low regions for colorectal cancer, and 11 high-high regions and one low-high region and 8 low-low region for liver cancer;the local G indexes disclosed 3 cold spots and one hot spots for esophageal caner,4 cold spots and 2 hot spots for gastric cancer,6 cold spots and one hot spot for colorectal cancer, and one cold spot and 2 hot spots for liver cancer, respectively. Conclu- sion The incidences of four main digestive system cancer show a non-random spatial distribution at township level in the studied area of Fujian province and there are cancer specific hot spots, cold spots and crisscross regions with high and low incidence of the four cancers.

关 键 词：消化系统肿瘤 空间自相关 空间流行病学 

分 类 号：R735[医药卫生—肿瘤]