负压封闭引流技术对糖尿病足再发溃疡疗效的研究  

Effect of negative-pressure wound therapy on diabetic foot with recurrence ulcers

作　　者：李惠东[1] 杨乾坤[1] 李书慧[1] 张清君[1] 李婷[1] 

机构地区：[1]郑州大学第一附属医院外科门诊,河南郑州450052

出　　处：《中华医院感染学杂志》2017年第8期1792-1794,共3页Chinese Journal of Nosocomiology

摘　　要：目的探讨负压封闭引流技术对糖尿病足再发溃疡的疗效,为临床治疗提供参考依据。方法收集医院2012年3月-2016年1月糖尿病足患者123例,其中,初发溃疡组57例,再发溃疡组66例,两组均接受负压封闭引流技术治疗,治疗3~13周后观察其创面愈合情况,对比两组疗效。结果糖尿病足初发组治愈率为36.84%,再发组治愈率为19.70%,两组治愈率的差异有统计学意义(P<0.05);糖尿病足初发组无效率为7.02%,糖尿病足再发组无效率为21.21%,两组无效率的差异有统计学意义(P<0.05)。结论负压封闭引流技术对糖尿病足再发溃疡的疗效较初发溃疡差,可能与再发组糖尿病病程长、血糖控制差、外周动脉疾病发生率高、混合感染率高等相关。OBJECTIVE To explore the effect of negative-pressure wound therapy on diabetic foot with recurrence ulcers, so as to provide references for clinical treatment. METHODS A total of 123 cases of diabetic foot patients from Mar. 2012 to Jan. 2016 were collected, including 57 cases in starting ulcer group and 66 cases in recurrence ulcer group. Patients in the two groups were treated with negative-pressure wound therapy, the wound healing situations at 3 ~ 13 weeks after treatment were observed, and the effects of the two groups were compared. RESULTS The cure rates were 36.84% in starting ulcer group, and 19.70% in recurrence ulcer group, and the difference of the two groups was significant （P〈0. 05）. The inefficiency rates were 7.02% in starting ulcer group, and 21.21 ~ in recurrence ulcer group, and the difference of the two groups was significant （P〈0.05）. CONCLUSION Compared to the starting ulcer, the effect of negative-pressure wound therapy on diabetic foot with recurrence ulcers is poor, which may be associated with the long duration of diabetes, high glycemic level, high rate of peripheral artery disease and high rate of mix infection.

关 键 词：糖尿病足 再发溃疡 负压封闭引流技术 

分 类 号：R735.1[医药卫生—肿瘤]