生物催化在农药生产中的应用及发展潜力  

Application and Potential of Biocatalysis in the Pesticide Industry

作　　者：陆跃乐 李剑锋[1] 陈小龙[1] 李忠 范永仙[1] 沈寅初[1] LU Yue-le LI Jian-feng CHEN Xiao-long LI Zhong FAN Yong-xian SHEN Yin-chu(Zhejiang University of Technology, Institution of Fermentation Engineering Research, Hangzhou 310014, China Zhejiang Tonglu Huifeng Biotechnology Co., Ltd., Hangzhou 311500, China)

机构地区：[1]浙江工业大学发酵工程研究所,杭州310014 [2]浙江省桐庐汇丰生物科技有限公司,杭州311500

出　　处：《农药》2017年第4期235-238,共4页Agrochemicals

基　　金：浙江省公益性项目(2015C34003);国家自然科学基金(21572206)

摘　　要：农药在农业中具有独一无二的地位,尽管传统的化学合成方法在农药生产中占有极高的比例。化学方法也存在诸多问题,如操作复杂、成本高以及环境污染等。近年来,生物催化所表现出的高选择性、反应条件温和、低毒低污染等特点逐渐受到许多企业的青睐,其在农药生产中的应用比重也持续增加。综述了生物催化在手性农药的去消旋化、不对称合成等方面的研究以及应用情况。Pesticides have a unique posit ion in agriculture. Although pesticide production have occupied sizable proportion in traditional chemical synthesis, chemical synthesis methods exist many problems such as complicated operation, high cost, environmental pollution and so on. In recent years, the features of biocatalysis showed mild reaction conditions, high selectivity, low toxicity, low pollution, and was gradually favored by many companies. Its share in pesticide production has continued to increase. In this paper, the biocatalytic chiral pesticides deracemization, asymmetric synthesis and other aspects of researches and applications were reviewed.

关 键 词：农药 生物催化 去消旋化 不对称合成 

分 类 号：TQ450.1[化学工程—农药化工] O643.3[理学—物理化学]