中药联合“四联疗法”治疗Hp阳性慢性胃炎疗效观察  

Efficacy of Chinese Medicine Combined with Fixed Quadruple Therapy on Hp Positive Chronic Gastritis

作　　者：汪楠[1] 王垂杰[2] 李玉锋[2] 

机构地区：[1]辽宁中医药大学第一临床学院,沈阳110032 [2]辽宁中医药大学附属医院消化内科,沈阳110032

出　　处：《中国中西医结合杂志》2017年第4期406-409,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家科技重大专项(No.2010ZX09401-304);2012年辽宁省中医药临床学(专科)能力建设项目(No.2012-lnzyxzk-03)

摘　　要：目的观察中药联合"四联疗法"治疗Hp阳性慢性胃炎疗效。方法选择375例Hp阳性慢性胃炎患者,随机分为对照组(A组)、辨证组(B组)、抗幽合剂组(C组)。各组给予西药四联疗法;B组加中医辨证论治汤剂;C组加抗幽合剂。每组疗程均为14天,记录患者治疗前后症状积分,停药1个月后复查Hp阳性情况。结果与A组比较,B、C组Hp根除率升高(P<0.01,P<0.05)。与本组治疗前比较,各组治疗后各症状积分及总积分均降低(P<0.01)。与A组同期比较,B、C组治疗后总积分改善率明显升高(P<0.05)。结论辨证应用中药汤剂、中药固定方剂联合"四联疗法"可有效提高Hp根除率。Objective To study the efficacy therapy＂ on Hp positive chronic gastritis. Methods of Chinese medicine combined with fixed ＂quadruple Totally 375 patients with Hp positive chronic gastritis were assigned to the control group （group A）, syndrome differentiation group （group B） and Kangyou Mixture group （group C）. All the patients received quadruple therapy; patients in group B took TCM De- coction ; patients in group C took Kangyou Mixture. The treatment lasted for 14 days intotal. The symptom scores were observed before and after treatment. The positive rate of Hp was reviewed at 1 month after treatment. Results The eradication rates of Hp in group B and C were increased compared with group A （P 〈0.01, P 〈0.05）. The symptom scores of each group were decreased after treatment （P 〈0.01 ）. Compared with group A, the improvement rate of symptom scores were increased in both Group B and Group C after treatment（P 〈0.05）. Conclusion Chinese medicine combined with fixed ＂quadruple thera- py＂ could improve the eradication rate of Hp.

关 键 词：幽门螺杆菌 中西医结合 辨证 抗幽合剂 

分 类 号：R573.3[医药卫生—消化系统]