Marchiafava-Bignami病合并胼胝体外病灶的MRI表现  

MRI appearance of marechiafava-bignami disease involving extracallosal lesions

作　　者：吴杰 王学建 宋玲玲[3] 张体江[4] 肖辉 眭贺[3] 吴忠纯 刘英 

机构地区：[1]贵州省六盘水市人民医院影像科,贵州六盘水553000 [2]贵州省贵航集团贵阳医院放射科,贵州贵阳550000 [3]贵州医科大学附属医院放射科,贵州贵阳550000 [4]贵州省遵义医学院附属医院放射科,贵州遵义563000

出　　处：《医学影像学杂志》2017年第4期591-595,共5页Journal of Medical Imaging

摘　　要：目的分析原发性胼胝体变性合并胼胝体外病灶的MRI表现。方法回顾性分析68例经临床诊断MBD患者合并胼胝体外病灶的MRI表现。结果 68例患者中,28例急性起病,17例亚急性起病,23例慢性起病.68例MRI均可见胼胝体对称性病灶合并大脑半球白质、桥臂、皮质、内囊、前连合异常信号灶,胼胝体病灶与胼胝体外病灶MRI信号类似,DWI胼胝体与大脑半球白质同时发现局部高亮信号。结论 MBD患者发病可累及胼胝体及胼胝体外,胼胝体外病灶可能是MBD急性加重的一种起病形式,及时治疗可以缓解。MRI能准确显示和发现病灶,对早期诊断及治疗、估计预后具有重要价值。Objective To investigate the appearance of marechiafava-bignami disease （MBD） affect extracallosal. Methods MR findings of 68 patients in marechiafava-bignami disease with bilateral extracallosal lesions were retrospectively analyzed. Results Acute onset （ n = 28）, subaeute onset （ n = 17 ）, and choronic onset （ n = 23 ） were found in the 68 cases. All patients showed symmetrical signal abnormality in the corpus callosum and both hemispheric white matter,cortical gray matter, middle cerebellar peduncles, posterior internal capsule, and anterior commissure. MRI revealed iso-or hypo-intensity on T1WI, hyper intensity on T2 WI and FLAIR and DWI. There were the same intense signals in both corpus callosum and ertracallosal. DWI showed equal bright signal intensity located in the corpus eallosum and hemisphere white matter. Conclusion Extracallosal affected areas in MBD were probably demonstrated by MR image during the acute exacerbation phase. MR imaging is helpful in early diagnosis and management of MBD.

关 键 词：胼胝体变性 胼胝体 磁共振成像 

分 类 号：R742.8[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]