不可切除性肝门胆管癌的非手术治疗进展  

Non-surgical Treatment of Unresectable Hilar Cholangiocarcinoma

作　　者：钟振东[1] 易为民[1] 彭创[1] ZHONG Zhendong YI Weimin PENG Chuang.(Department of Hepatobiliary Surgery, Hunan Provincial People＇s Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha 410005, China)

机构地区：[1]湖南省人民医院暨湖南师范大学第一附属医院肝胆外科,长沙410005

出　　处：《医学综述》2017年第8期1595-1598,1603,共5页Medical Recapitulate

摘　　要：肝门胆管癌是肝外胆管细胞癌最常见的类型,依据不同的临床分期,其治疗方式和预后均存在较大的差异,目前对于肝门胆管癌的治疗呈现多样化发展。根治性切除是治愈的唯一方法,而实际情况下,大部分晚期患者发现时已无法行根治性手术治疗,故辅助治疗方式对于不可切除性肝门胆管癌患者的预后起到至关重要的作用。随着介入技术和辅助设备的进步,不可切除性肝门胆管癌的非手术治疗方式得到多样化发展。支架置入能够有效解除胆管梗阻,门静脉栓塞能有效增加剩余肝体积,125I和光动力学疗法一定程度上抑制了肿瘤的生长。Hilar eholangiocarcinoma is the most prevalent type of extrahepatic cholangiocarcinoma, and the treatment methods and prognosis are different based on different clinical stages. The treatment of hilar cholangiocarcinoma has diversified development. Radical resection is the only way to cure, but in practice, most of the patients with advanced disease cannot be treated with radical surgery. Therefore, adjuvant therapy plays an important role in the prognosis of patients with unreseetable hilar cholangiocarcinoma. With the development of interventional techniques and auxiliary devices, the non-operative treatment of unresectable hilar cholangiocarcinoma has been diversified. Stent implantation can effectively relieve biliary obstruction, portal vein embolization can effectively increase the residual liver volume, and ^125I and photodynamic therapy can inhibit the growth of tumor to some extent.

关 键 词：肝门胆管癌 不可切除 非手术治疗 

分 类 号：R735.8[医药卫生—肿瘤]