胃镜下胆汁反流诱导胃黏膜肠化生的探究  

A study of gastrointestinal metaplasia induced by bile reflux under gastroscope

作　　者：张雁[1] 李哲华[1] 熊阿琴[1] 

机构地区：[1]广州市番禺区中医院,广东广州511400

出　　处：《中国中西医结合消化杂志》2017年第3期223-225,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：[目的]研究胃镜下胆汁反流诱导胃黏膜肠化生相关性探究。[方法]选取2005年1月1日~2005年12月31日我院门诊及住院胃镜检查人员共4 795人,以50周岁为界分为低龄组(1 310人)、高龄组(3 485人)。低龄组与高龄组中胆汁反流性与非胆汁反流性中发生肠化生几率进行对比,通过卡方检验分析胆汁反流性与肠化生的相关性。[结果]按积分RDQ≥13为症状标准,伴胆汁反流低龄组,胃粘膜肠化发生率显著高于不伴胆汁反流低龄组、高龄组;伴胆汁反流高龄组,胃粘膜肠化发生率显著高于不伴胆汁反流高龄组、低龄组,差异均有统计学意义(P<0.01)。[结论]胃镜下诊断胆汁反流性胃炎与病理诊断胃黏膜组织肠上皮化生有一定相关性。[Objective]To study the relationship between gastrointestinal metaplasia induced by bile re- flux under gastroscope [Methods]A total of 4795 people were enrolled in the outpatient and inpatient en- doscopy from January 1,2005 to December 31,2005.50 years of age as the boundary,the patients were di- vided into the younger age group （1310 persons） and the elderly group （3485 persons）. The incidence of in- testinal metaplasia in bile regurgitation and non-bile reflux was compared between young and elderly group. The correlation between bile reflux and intestinal metaplasia was analyzed by chi-square test. IRe- suits]The RDQ-13 was the symptom standard, the incidence of intestinal metaplasia was significantly higher in the bile reflux younger group and the bile reflux group than in the bile reflux group and the elder group. The intestinal metaplasia of gastric mucosa （P〈0. 01）,which was significantly higher than that in the elderly without bile reflux and the younger age group （P〈0. 01）. [Conclusion]The diagnosis of bile reflux gastritis by endoscopy is associated with pathological diagnosis of intestinal metaplasia in gastric mucosa.

关 键 词：胃黏膜 肠化生 胆汁反流性胃炎 胃镜 

分 类 号：R573.3[医药卫生—消化系统]