机构地区:[1]Department of Neurology,Children’s Hospital of Fudan University,Shanghai 201102,China [2]Department of Psychiatry,The Second Xiangya Hospital of Central South University,Changsha 410008,China [3]School of Public Health,Harbin Medical University,Harbin 150081,China [4]Child Development Center,The Third Affiliated Hospital,Sun Yat-Sen University,Guangzhou 510000,China [5]State Key Laboratory of Medical Genetics,Changsha 400078,China [6]Department of Child Healthcare,Children’s Hospital of Fudan University,Shanghai 201102,China [7]Children’s Hospital of Fudan University,Shanghai 201102,China [8]Division of Medical Genetics,Department of Pediatrics and Neurobiology,Duke University School of Medicine,Durham,NC 27710,USA [9]Institute on Development and Disability,Oregon Health and Science University,Portland,OR 97239,USA [10]Department of Clinical Epidemiology,Children’s Hospital of Fudan University,Shanghai 201102,China [11]Pediatric Department of Guizhou Provincial People’s Hospital,Guiyang 550002,China
出 处:《Neuroscience Bulletin》2017年第2期175-182,共8页神经科学通报(英文版)
基 金:supported by the National Health and Family Planning Commission of the People’s Republic of China(201302002;Clinical Trials.gov number NCT 02200679);the Shanghai International Cooperation Ministry of Science Projects(14430712200);the Development Project of Shanghai Peak Discipline-Integrated Chinese and Western Medicine
摘 要:The purpose of this study was to explore the psychometric properties of the Chinese version of the autism spectrum rating scale(ASRS). We recruited 1,625community-based children and 211 autism spectrum disorder(ASD) cases from 4 sites, and the parents of all participants completed the Chinese version of the ASRS. A robust weighted least squares means and variance adjusted estimator was used for exploratory factor analysis. The3-factor structure included 59 items suitable for the current sample. The item reliability for the modi?ed Chinese version of the ASRS(MC-ASRS) was excellent. Moreover,with 60 as the cut-off point, receiver operating characteristic analysis showed that the MC-ASRS had excellent discriminate validity, comparable to that of the unmodi?ed Chinese version(UC-ASRS), with area under the curve values of 0.952(95% CI: 0.936–0.967) and 0.948(95% CI:0.930–0.965), respectively. Meanwhile, the con?rm factor analysis revealed that MC-ASRS had a better construct validity than UC-ASRS based on the above factor solution in another children sample. In conclusion, the MC-ASRS shows better ef?cacy in epidemiological screening for ASD in Chinese children.The purpose of this study was to explore the psychometric properties of the Chinese version of the autism spectrum rating scale(ASRS). We recruited 1,625community-based children and 211 autism spectrum disorder(ASD) cases from 4 sites, and the parents of all participants completed the Chinese version of the ASRS. A robust weighted least squares means and variance adjusted estimator was used for exploratory factor analysis. The3-factor structure included 59 items suitable for the current sample. The item reliability for the modi?ed Chinese version of the ASRS(MC-ASRS) was excellent. Moreover,with 60 as the cut-off point, receiver operating characteristic analysis showed that the MC-ASRS had excellent discriminate validity, comparable to that of the unmodi?ed Chinese version(UC-ASRS), with area under the curve values of 0.952(95% CI: 0.936–0.967) and 0.948(95% CI:0.930–0.965), respectively. Meanwhile, the con?rm factor analysis revealed that MC-ASRS had a better construct validity than UC-ASRS based on the above factor solution in another children sample. In conclusion, the MC-ASRS shows better ef?cacy in epidemiological screening for ASD in Chinese children.
关 键 词:Autism spectrum disorder Screening Epidemiology Exploratory factor analysis Children
分 类 号:R749.94[医药卫生—神经病学与精神病学]
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